Evidence map›Paper›PMID 33981443›Full record

ArticleVeterinary record open2021

Faecal proteome in clinically healthy dogs and cats: Findings in pooled faeces from 10 cats and 10 dogs.

Matteo Cerquetella, Andrea Marchegiani, Sara Mangiaterra, Giacomo Rossi, Alessandra Gavazza, Beniamino Tesei, Andrea Spaterna, Gianni Sagratini, Massimo Ricciutelli, Valeria Polzonetti and 2 more

Open access · goldAbstract read
In one paragraph

Article in Veterinary record open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Evaluation of the Fecal Proteome in Healthy and Diseased Cheetahs (Animals : an open access journal from MDPI · 2022
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Matteo CerquetellaSchool of Biosciences and Veterinary Medicine University of Camerino Matelica MC Italy.ORCID https://orcid.org/0000-0001-9471-0756
Andrea MarchegianiSchool of Biosciences and Veterinary Medicine University of Camerino Matelica MC Italy.ORCID https://orcid.org/0000-0002-3629-0391
Sara MangiaterraSchool of Biosciences and Veterinary Medicine University of Camerino Matelica MC Italy.
Giacomo RossiSchool of Biosciences and Veterinary Medicine University of Camerino Matelica MC Italy.
Alessandra GavazzaSchool of Biosciences and Veterinary Medicine University of Camerino Matelica MC Italy.
Beniamino TeseiSchool of Biosciences and Veterinary Medicine University of Camerino Matelica MC Italy.
Andrea SpaternaSchool of Biosciences and Veterinary Medicine University of Camerino Matelica MC Italy.
Gianni SagratiniSchool of Pharmacy University of Camerino Camerino MC Italy.
Massimo RicciutelliSchool of Pharmacy University of Camerino Camerino MC Italy.
Valeria PolzonettiSchool of Biosciences and Veterinary Medicine University of Camerino Matelica MC Italy.
Stefania PucciarelliSchool of Biosciences and Veterinary Medicine University of Camerino Matelica MC Italy.
Silvia VincenzettiSchool of Biosciences and Veterinary Medicine University of Camerino Matelica MC Italy.
Università di Camerino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the scientific literature, there are only a few manuscripts available on small animal faecal proteomics.

methodsIn the present pilot study, this evaluation was performed using pooled faecal samples from 10 clinically healthy dogs and, for the first time, in 10 clinically healthy cats by mean of two-dimensional electrophoresis followed by liquid chromatography-tandem mass spectrometry.

resultsOur results showed the presence of nine (albumin, alkaline phosphatase, chymotrypsin-C-like, cytosol aminopeptidase, elastase-3B/proteinase E, immunoglobulins and nuclear pore membrane glycoprotein 210) and 14 (albumin, caspase recruitment domain-containing protein, chymotrypsin-like, deleted in malignant brain tumours 1 protein-like, hypothetical protein LOC107375, immunoglobulin, kallikrein-1, superoxide dismutase, transthyretin precursor, interstitial collagenase-like) different proteins in canine and feline faeces, respectively.

conclusionThese preliminary findings document the presence of a range of proteins in the faeces of apparently healthy dogs and cats and may serve as a basis for larger, prospective studies to establish reference proteomic data against which diseased populations can be compared.

Indexed as

catdogfaecal proteomicshealthy pattern

Identifiers

PMID33981443
PMCPMC8110131
OpenAlexW3161039645

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.