Evidence map›Paper›PMID 33981306›Full record

ArticleFrontiers in immunology2021

Bactericidal/Permeability-Increasing Protein Preeminently Mediates Clearance of

Jomkuan Theprungsirikul, Sladjana Skopelja-Gardner, Ashley S Burns, Rachel M Wierzbicki, William F C Rigby

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jomkuan TheprungsirikulDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH, United States.
Sladjana Skopelja-GardnerDivision of Rheumatology, Department of Medicine, Geisel School of Medicine at Dartmouth, Lebanon, NH, United States.
Ashley S BurnsDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH, United States.
Rachel M WierzbickiDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH, United States.
William F C RigbyDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH, United States.
Dartmouth College · US

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3M
Understanding the role of RNA-binding protein mutations in cancerP20GM113132 · NIGMS · DARTMOUTH COLLEGE · PI MADDEN, DEAN R · 2016 to 2025
$25.9M
Olympus FV1200 Near Infrared Confocal MicroscopeS10OD021616 · OD · DARTMOUTH COLLEGE · PI STAN, RADU VIRGIL · 2016 to 2016
$321k
NCI NIH HHS P30 CA023108NIGMS NIH HHS P20 GM113132NIH HHS S10 OD021616
6 · The paper itself

Abstract

Chronic

Indexed as

AnimalsAntimicrobial Cationic PeptidesBlood ProteinsCD18 AntigensCells, CulturedCytokinesFemaleFlow CytometryFluorescent Antibody TechniqueInflammationLungMaleMiceMice, Inbred C57BLMice, KnockoutNeutrophilsAntimicrobial Cationic Peptidesbactericidal permeability increasing proteinBlood ProteinsCD18 AntigensCytokinesReactive Oxygen SpeciesBactericidal/permeability-increasing protein (BPI)CD18inflammationinnate immunityneutrophilsopsonizationphagocytosisPseudomonas

Identifiers

PMID33981306
PMCPMC8107240
OpenAlexW3160553222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.