Evidence map›Paper›PMID 33981297›Full record

ArticleFrontiers in immunology2021

PMN-MDSC Frequency Discriminates Active Versus Latent Tuberculosis and Could Play a Role in Counteracting the Immune-Mediated Lung Damage in Active Disease.

Germana Grassi, Valentina Vanini, Federica De Santis, Alessandra Romagnoli, Alessandra Aiello, Rita Casetti, Eleonora Cimini, Veronica Bordoni, Stefania Notari, Gilda Cuzzi and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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  8. Article
  9. Suppressive myeloid cells in SARS-CoV-2 andFrontiers in immunology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Germana GrassiLaboratory of Cellular Immunology and Pharmacology, National Institute for infectious Diseases "Lazzaro Spallanzani"-IRCCS, Rome, Italy.
Valentina VaniniLaboratory of Translational Research, National Institute for infectious Diseases "Lazzaro Spallanzani"-IRCCS, Rome, Italy.
Federica De SantisDepartment of Biology, University of Rome "Tor Vergata", Rome, Italy.
Alessandra RomagnoliDepartment of Epidemiology, Preclinical Research, and Advanced Diagnostics, National Institute for Infectious Diseases 'Lazzaro Spallanzani'-IRCCS, Rome, Italy.
Alessandra AielloLaboratory of Translational Research, National Institute for infectious Diseases "Lazzaro Spallanzani"-IRCCS, Rome, Italy.
Rita CasettiLaboratory of Cellular Immunology and Pharmacology, National Institute for infectious Diseases "Lazzaro Spallanzani"-IRCCS, Rome, Italy.
Eleonora CiminiLaboratory of Cellular Immunology and Pharmacology, National Institute for infectious Diseases "Lazzaro Spallanzani"-IRCCS, Rome, Italy.
Veronica BordoniLaboratory of Cellular Immunology and Pharmacology, National Institute for infectious Diseases "Lazzaro Spallanzani"-IRCCS, Rome, Italy.
Stefania NotariLaboratory of Cellular Immunology and Pharmacology, National Institute for infectious Diseases "Lazzaro Spallanzani"-IRCCS, Rome, Italy.
Gilda CuzziLaboratory of Translational Research, National Institute for infectious Diseases "Lazzaro Spallanzani"-IRCCS, Rome, Italy.
Silvia MostiRespiratory Infectious Diseases Unit, National Institute for infectious Diseases "Lazzaro Spallanzani"-IRCCS, Rome, Italy.
Gina GualanoRespiratory Infectious Diseases Unit, National Institute for infectious Diseases "Lazzaro Spallanzani"-IRCCS, Rome, Italy.
Fabrizio PalmieriRespiratory Infectious Diseases Unit, National Institute for infectious Diseases "Lazzaro Spallanzani"-IRCCS, Rome, Italy.
Maurizio FrazianoDepartment of Biology, University of Rome "Tor Vergata", Rome, Italy.
Delia GolettiLaboratory of Translational Research, National Institute for infectious Diseases "Lazzaro Spallanzani"-IRCCS, Rome, Italy.
Chiara AgratiLaboratory of Cellular Immunology and Pharmacology, National Institute for infectious Diseases "Lazzaro Spallanzani"-IRCCS, Rome, Italy.
Alessandra SacchiLaboratory of Cellular Immunology and Pharmacology, National Institute for infectious Diseases "Lazzaro Spallanzani"-IRCCS, Rome, Italy.
Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB), due to

Indexed as

Latent TuberculosisLeukocyte CountAdultBiomarkersDiagnosis, DifferentialFemaleHost-Pathogen InteractionsHumansMaleMiddle AgedMonocytesMycobacterium tuberculosisMyeloid-Derived Suppressor CellsNeutrophilsROC CurveSeverity of Illness IndexBiomarkersactive TBLTBI (latent TB infections)MDSC (myeloid-derived suppressor cell)monocytestuberculosis

Identifiers

PMID33981297
PMCPMC8107479
OpenAlexW3159266887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.