Evidence map›Paper›PMID 33981207›Full record

ArticleFrontiers in human neuroscience2021

Safety and Tolerability of Burst-Cycling Deep Brain Stimulation for Freezing of Gait in Parkinson's Disease.

Joshua K Wong, Wei Hu, Ryan Barmore, Janine Lopes, Kathryn Moore, Joseph Legacy, Parisa Tahafchi, Zachary Jackson, Jack W Judy, Robert S Raike and 4 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in human neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07410598 (Safety and Tolerability of Patterned Stimulation for DBS in the Home Setting), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07410598 narecruitingnot on this mapstarted 2026, after this paper: background citation

Safety and Tolerability of Patterned Stimulation for DBS in the Home Setting

TypeinterventionalSponsorUniversity of FloridaRan2026 to 2028Enrolled60ConditionsParkinson Disease, Deep Brain StimulationArmsBiphasic deep brain stimulation, Conventional deep brain stimulation, Theta burst deep brain stimulation, Multi frequency deep brain stimulation
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Topography of Regional Cerebral GABAThe European journal of neuroscience · 2026
    Article
  3. Review
  4. Article
  5. Pilot Study of Acute Behavioral Effects of Pallidal Burst Stimulation in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2024
    Article
  6. Advances in Deep Brain Stimulation: From Mechanisms to Applications.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Review
  7. Review
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Joshua K WongDepartment of Neurology, Norman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
Wei HuDepartment of Neurology, Norman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
Ryan BarmoreBanner Health Physicians Colorado, Loveland, CO, United States.
Janine LopesDepartment of Neurology, Norman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
Kathryn MooreDepartment of Neurology, Norman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
Joseph LegacyDepartment of Neurology, Norman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
Parisa TahafchiDepartment of Electrical and Computer Engineering, University of Florida, Gainesville, FL, United States.
Zachary JacksonDepartment of Electrical and Computer Engineering, University of Florida, Gainesville, FL, United States.
Jack W JudyDepartment of Neurology, Norman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
Robert S RaikeRestorative Therapies Group Implantables, Research and Core Technology, Medtronic, Minneapolis, MN, United States.
Anson WangDepartment of Neurology, Norman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
Takashi TsuboiDepartment of Neurology, Norman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
Michael S OkunDepartment of Neurology, Norman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
Leonardo AlmeidaDepartment of Neurology, Norman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
University of Florida · USBanner Health · USMedtronic (United States) · USNagoya University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

burst cyclingdeep brain stimulationfreezing of gaitglobus pallidum internaGPiParkinson’s diseaseSTNsubthalamic nucleus

Identifiers

PMID33981207
PMCPMC8109241
OpenAlexW3159546550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.