ReviewJournal of blood medicine2021
Primary Pancreatic Lymphoma: Recommendations for Diagnosis and Management.
Review in Journal of blood medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 31 citations in OpenAlex.
- Primary hepatopancreatobiliary lymphoma: epidemiology, clinical features, and treatment outcomes.Scientific reports · 2026Article
- Epidemiological landscape and clinical heterogeneity of primary pancreatic lymphoma: a population-based study.Cancer causes & control : CCC · 2026Article
- Imaging of non-ductal pancreatic neoplasms.Abdominal radiology (New York) · 2026Review
- Article
- Solid pancreatic lesions: etiology, morphology and utility of macroscopic on-site evaluation in predicting good yield of endoscopic ultrasound-guided biopsy.Przeglad gastroenterologiczny · 2025Article
- A peculiar case of primary lymphoma of pancreas: A rare presentation of Hodgkin lymphoma.Oncoscience · 2025Article
- Primary pancreatic lymphoma: A case report and review of literature.World journal of clinical oncology · 2024Article
- Differential Diagnosis of Pancreatic Cancer and its Mimicking Lesions.Journal of the Korean Society of Radiology · 2024Review
- Primary pancreatic peripheral T-cell lymphoma: A case report.World journal of gastrointestinal oncology · 2024Article
- Acute Pancreatitis Revealing a Diagnosis of Diffuse Large B-Cell Lymphoma.ACG case reports journal · 2024Article
- Primary pancreatic lymphoma: Histopathological pattern of 8 cases.Saudi medical journal · 2024Article
- Primary pancreatic peripheral T-cell lymphoma-not otherwise specified mimicking acute pancreatitis: A case report and review of literature.Clinical case reports · 2024Article
- Primary pancreatic lymphoma: Report of 4 cases with literature review.Radiology case reports · 2024Article
- Article
- Burkitt Lymphoma Presenting as Obstructive Jaundice: A Case Report and Literature Review.Cureus · 2023Article
- Article
- Article
- Primary hepatopancreatobiliary lymphoma: Pathogenesis, diagnosis, and management.Frontiers in oncology · 2022Review
- Solid pancreatic masses in children: A review of current evidence and clinical challenges.Frontiers in pediatrics · 2022Review
- A Rare Case of Primary B-Cell Lymphoma of the Pancreas.Journal of investigative medicine high impact case reportsArticle
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrimary pancreatic lymphoma (PPL) is a rare disease representing 0.1% of all malignant lymphomas, which lacks well-defined diagnostic and therapeutic protocols. We conducted a systematic review to analyze demographic, diagnostic and therapeutic features of PPL.
methodsThis review identified small series and single case reports. Sources were MEDLINE, PubMed, and the Cochrane library from January 2001 to December 2020. Data were screened, extracted and the risk of bias analyzed by three independent reviewers.
resultsA total of 107 eligible papers (17 small series, 90 single case reports) describing 266 patients were identified. Patients had a median age of 53.1 (range 3-86) years and were males in 64.6% of cases. Abdominal pain and jaundice were the most common presenting symptoms, affecting 75.3% and 41.8% of patients, respectively. PPL had a median size of 60.6 mm (range 16-200) and it was localized in the pancreatic head in 63.7% of cases. At diagnosis most patients underwent ultrasonography followed by computed tomography. PPL typically showed low echogenicity, and lower contrast enhancement than solid tumors. Histopathological specimens were obtained by percutaneous or endoscopic biopsies in 47.7% of patients; abdominal surgery was performed in 33.5% of cases. Overall, diffuse large B-cell lymphoma was the most frequent histological diagnosis (53.6%). However, patients aged <18 years were affected by Burkitt lymphoma in 52.4% of cases. Most patients (53.6%) received immunochemotherapy (IC) or IC plus radiotherapy (14%). Demolitive surgery appeared to be associated with impaired survival. Central nervous system (CNS) relapse or progression was observed in 20% of patients.
conclusionPPL is a rare entity, with some peculiar features at modern imaging. For diagnostic purposes percutaneous or endoscopic biopsies might be preferable, as opposed to surgery. No definite data is available about the optimal treatment, which should be tailored on the histological type and associated with CNS prophylaxis.
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