Evidence map›Paper›PMID 33981085›Full record

ReviewNature reviews. Immunology2021

CD8

Miguel Reina-Campos, Nicole E Scharping, Ananda W Goldrath

Open access · greenAbstract readReview
In one paragraph

Review in Nature reviews. Immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 415 papers.

0numbers the graph read from it
0cells of the map it votes in
415citing papers in PubMed
28.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

415 citing papers in PubMed, 582 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Renaissance of antiviral CD8Nature reviews. Immunology · 2026
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. RNF149/RBM25/MYC/PD-L1 axis promotes CD8Cellular oncology (Dordrecht, Netherlands) · 2026
    Article
  18. Article
  19. Review
  20. Review

355 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Miguel Reina-Campos *Division of Biological Sciences, Section of Molecular Biology, University of California, San Diego, La Jolla, CA, USA.
Nicole E Scharping *Division of Biological Sciences, Section of Molecular Biology, University of California, San Diego, La Jolla, CA, USA.
Ananda W GoldrathDivision of Biological Sciences, Section of Molecular Biology, University of California, San Diego, La Jolla, CA, USA. agoldrath@ucsd.edu.ORCID http://orcid.org/0000-0002-5900-508X
University of California San Diego · US

Funding

Single-Cell Transcriptomic and Epigenetics CoreP01AI132122 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI YEO, EUGENE WEI-MING · 2018 to 2022
$9.8M
T cell maintenance: molecular mediators of the TCR-derived survival signalR01AI067545 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GOLDRATH, ANANDA W · 2006 to 2021
$6.1M
Regulation of T cell immunity to viral infectionR01AI072117 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GOLDRATH, ANANDA W · 2008 to 2022
$5.4M
T cell maintenance: molecular mediators of T cell differentiation and survivalR37AI067545 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ananda W Goldrath · 2022 to 2026
$3.0M
Tumor-infiltrating T cell metabolic dysfunction and genetic reprogramming for effective immunotherapyK00CA222711 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SCHARPING, NICOLE E · 2020 to 2023
$360k
NCI NIH HHS K00 CA222711NIAID NIH HHS P01 AI132122NIAID NIH HHS R01 AI067545NIAID NIH HHS R01 AI072117NIAID NIH HHS R37 AI067545
6 · The paper itself

Abstract

Cytotoxic CD8

Indexed as

AnimalsCD8-Positive T-LymphocytesCell DifferentiationHumansInfectionsLymphocyte ActivationNeoplasmsT-Lymphocytes, Cytotoxic

Identifiers

PMID33981085
PMCPMC8806153
OpenAlexW3161479873

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.