Evidence map›Paper›PMID 33980653›Full record

ArticleJournal of clinical microbiology2021

A Molecular-Beacon-Based Multiplex Real-Time PCR Assay To Distinguish Mycobacterium abscessus Subspecies and Determine Macrolide Susceptibility.

Salvatore A E Marras, Liang Chen, Elena Shashkina, Rebecca M Davidson, Michael Strong, Charles L Daley, Barry N Kreiswirth

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Frontiers in cellular and infection microbiology · 2026
    Pooled it
  2. Article
  3. DetectingAntibiotics (Basel, Switzerland) · 2026
    Article
  4. Article
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  6. Antimicrobial agents and chemotherapy · 2024
    Article
  7. CutaneousClinical, cosmetic and investigational dermatology · 2024
    Article
  8. Article
  9. Short SignatureMicrobiology spectrum · 2022
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Salvatore A E Marras *Public Health Research Institute Center, New Jersey Medical School, Rutgers University, Newark, New Jersey, USA.
Liang Chen *Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA.
Elena ShashkinaCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA.
Rebecca M DavidsonCenter for Genes, Environment and Health, National Jewish Health, Denver, Colorado, USA.
Michael StrongCenter for Genes, Environment and Health, National Jewish Health, Denver, Colorado, USA.
Charles L DaleyDepartment of Medicine, National Jewish Health, Denver, Colorado, USA.
Barry N KreiswirthCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA.
Hackensack Meridian Health · USNational Jewish Health · USRutgers, The State University of New Jersey · US

Funding

Dissecting the molecular targets to overcome beta-lactam resistance in M. abscessus complexR01AI141805 · NIAID · HACKENSACK UNIVERSITY MEDICAL CENTER · PI BARRY Neal KREISWIRTH · 2019 to 2026
$5.1M
Background free amplified single-molecule FISH for in situ and flow cytometric applicationsR01CA227291 · NCI · RBHS-NEW JERSEY MEDICAL SCHOOL · PI TYAGI, SANJAY · 2018 to 2022
$2.8M
NCI NIH HHS R01 CA227291NIAID NIH HHS R01 AI141805
6 · The paper itself

Abstract

Mycobacterium abscessus is a rapidly growing nontuberculous mycobacterial species that comprises three subspecies: M. abscessus subsp. abscessus, M. abscessus subsp. massiliense, and M. abscessus subsp. bolletii. These predominantly environmental microorganisms have emerged as life-threatening chronic pulmonary pathogens in both immunocompetent and immunocompromised patients, and their acquisition of macrolide resistance due to the

Indexed as

Mycobacterium abscessusMycobacterium Infections, NontuberculousAnti-Bacterial AgentsClarithromycinDrug Resistance, BacterialHumansMacrolidesMicrobial Sensitivity TestsReal-Time Polymerase Chain ReactionAnti-Bacterial AgentsClarithromycinMacrolidesmacrolide resistancemolecular beaconMycobacterium abscessus

Identifiers

PMID33980653
PMCPMC8373218
OpenAlexW3162815686

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.