Evidence map›Paper›PMID 33980594›Full record

ArticleJournal of virology2021

Inhibition of Antiviral Innate Immunity by Foot-and-Mouth Disease Virus L

Chao Sui, Dandan Jiang, Xiangju Wu, Sidang Liu, Feng Li, Li Pan, Xiaoyan Cong, Juntong Li, Dongwan Yoo, Daniel L Rock and 4 more

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Mutation of FMDV LFrontiers in veterinary science · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 3 countries.

Chao SuiShandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China.
Dandan JiangShandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China.
Xiangju WuShandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China.
Sidang LiuShandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, College of Animal Science and Technology, Shandong Agricultural University, Tai'an, Shandong, China.
Feng LiDepartment of Biology and Microbiology, South Dakota State University, Brookings, South Dakota, USA.
Li PanState Key Laboratory of Veterinary Etiological Biology, National Foot and Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
Xiaoyan CongShandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China.
Juntong LiShandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China.
Dongwan YooDepartment of Pathobiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Daniel L RockDepartment of Pathobiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Laura C MillerVirus and Prion Research Unit, National Animal Disease Center, United States Department of Agriculture, Agricultural Research Service, Ames, Iowa, USA.
Changhee LeeAnimal Virology Laboratory, School of Life Sciences, BK21 plus KNU Creative BioResearch Group, Kyungpook National University, Daegu, Republic of Korea.
Yijun DuShandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China.
Jing QiShandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China.
Shandong Academy of Agricultural Sciences · CNUniversity of Illinois Urbana-Champaign · USAgricultural Research Service · USKyungpook National University · KRLanzhou Veterinary Research Institute · CNShandong Agricultural University · CNSouth Dakota State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Foot-and-mouth disease virus (FMDV) is the pathogen of foot-and-mouth disease (FMD), which is a highly contagious disease in cloven-hoofed animals. To survive in the host, FMDV has evolved multiple strategies to antagonize host innate immune responses. In this study, we showed that the leader protease (L

Indexed as

2',5'-Oligoadenylate SynthetaseAnimalsApoptosisCell LineCricetinaeDogsEndopeptidasesEndoribonucleasesFoot-and-Mouth DiseaseFoot-and-Mouth Disease VirusHaplorhiniHEK293 CellsHumansImmune EvasionImmunity, InnateMadin Darby Canine Kidney Cells2-5A-dependent ribonuclease2',5'-Oligoadenylate SynthetaseEndopeptidasesEndoribonucleasesleader proteinase, foot-and-mouth disease virusantagonistic mechanism.FMDVfoot-and-mouth disease virusISGsLproRNase L

Identifiers

PMID33980594
PMCPMC8274615
OpenAlexW3162416912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.