Evidence map›Paper›PMID 33980491›Full record

ArticleScience advances2021

Yeast volatiles double starvation survival in

Yuan Luo, Jacob C Johnson, Tuhin S Chakraborty, Austin Piontkowski, Christi M Gendron, Scott D Pletcher

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yuan LuoDepartment of Molecular and Integrative Physiology and the Geriatrics Center, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-6898-5710
Jacob C JohnsonDepartment of Molecular and Integrative Physiology and the Geriatrics Center, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-3431-4337
Tuhin S ChakrabortyDepartment of Molecular and Integrative Physiology and the Geriatrics Center, University of Michigan, Ann Arbor, MI, USA.
Austin PiontkowskiDepartment of Molecular and Integrative Physiology and the Geriatrics Center, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-8922-6545
Christi M GendronDepartment of Molecular and Integrative Physiology and the Geriatrics Center, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-9246-1036
Scott D PletcherDepartment of Molecular and Integrative Physiology and the Geriatrics Center, University of Michigan, Ann Arbor, MI, USA. spletch@umich.edu.ORCID 0000-0002-4812-3785
University of Michigan · US

Funding

Modulation of aging by Sensory PerceptionR01AG030593 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PLETCHER, SCOTT · 2007 to 2025
$6.1M
Modulation of aging through mechanisms of nutrient demand and rewardR37AG051649 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCOTT PLETCHER · 2021 to 2026
$2.3M
The role of neural signaling pathways in costs of reproduction on agingR01AG063371 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PLETCHER, SCOTT, PROMISLOW, DANIEL EDWARD · 2019 to 2023
$1.9M
Modulation of aging through mechanisms of nutrient demand and rewardR01AG051649 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PLETCHER, SCOTT · 2016 to 2020
$1.6M
NIA NIH HHS R01 AG030593NIA NIH HHS R01 AG051649NIA NIH HHS R01 AG063371NIA NIH HHS R37 AG051649
6 · The paper itself

Abstract

Organisms make decisions based on the information they gather from their environment, the effects of which affect their fitness. Understanding how these interactions affect physiology may generate interventions that improve the length and quality of life. Here, we provide evidence that exposure to live yeast volatiles during starvation significantly extends survival, increases activity, and slows the rate of triacylglyceride (TAG) decline independent of canonical sensory perception. We demonstrate that ethanol (EtOH) is one of the active components in yeast volatiles that influences these phenotypes and that EtOH metabolites mediate dynamic mechanisms to promote

Indexed as

Drosophila ProteinsStarvationAnimalsDrosophilaEthanolQuality of LifeSaccharomyces cerevisiaeDrosophila ProteinsEthanol

Identifiers

PMID33980491
PMCPMC8115925
OpenAlexW3160716953

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.