Evidence map›Paper›PMID 33980472›Full record

Observational studyGait & posture2022

Symptomatic individuals with Lumbar Disc Degeneration use different anticipatory and compensatory kinematic strategies to asymptomatic controls in response to postural perturbation.

Janet A Deane, Adrian K P Lim, Andrew T M Phillips, Alison H McGregor

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Gait & posture, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Janet A DeaneMSK LAB, Imperial College London, London, United Kingdom; School of Health Sciences, The University of Manchester and University of Manchester NHS Foundation Trust, Manchester, United Kingdom. Electronic address: janet.deane@manchester.ac.uk.
Adrian K P LimMSK LAB, Imperial College London, London, United Kingdom; Imaging Department, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.
Andrew T M PhillipsStructural Biomechanics, Department of Civil and Environmental Engineering, Imperial College London, United Kingdom.
Alison H McGregorMSK LAB, Imperial College London, London, United Kingdom.
Imperial College London · GBImperial College Healthcare NHS Trust · GBUniversity of Manchester · GB

Funding

Versus Arthritis 20172
6 · The paper itself

Abstract

backgroundLumbar Disc Degeneration (LDD) is associated with recurrent low back pain (LBP) (symptomatic). However, in some instances of LDD, people do not experience LBP (asymptomatic). RESEARCH QUESTION: As a step towards understanding why some people with LDD experience LBP and others do not, the primary aim of this study was to examine differences in anticipatory (APA) and compensatory postural adjustments (CPA), between symptomatic LDD patients (LDD pain) and asymptomatic LDD controls (LDD no pain) during postural perturbation. The secondary aim was to determine simultaneous differences in mental health, disability and quality of life status.

methods3 T MRI was used to acquire T2 weighted images (L1-S1) from LDD no pain (n = 34) and LDD pain groups (n = 34). In this observational study, responses to predicted and unpredicted forward perturbations were examined using three dimensional motion capture. A Mann Whitney U test was conducted to examine group differences in sagittal spine and lower limb kinematics (integrated angular displacements during four established APA and CPA time intervals), anxiety, depression, disability and quality of life.

resultsThe LDD pain group exhibited lower hip and knee displacements (p = 0.049-0.040) than the LDD no pain group during predicted and unpredicted perturbation. The LDD pain group also exhibited higher compensatory lumbar displacement than the LDD no pain group (p = 0.040-0.005) in the predicted condition but there was no difference observed in the unpredicted condition. The LDD pain group experienced higher levels of depression, anxiety and disability (p < 0.0001) and lower quality of life (p = 0.0001) than LDD controls. SIGNIFICANCE: Symptomatic LDD patients are different from LDD controls; they exhibit different kinematic strategies, levels of disability, anxiety, depression and quality of life. Effective care may benefit from evaluating and targeting these differences.

Indexed as

Intervertebral Disc DegenerationLow Back PainBiomechanical PhenomenaHumansLumbar VertebraeQuality of LifeBack painKinematicsLumbar degenerationMotion capturePostural control

Identifiers

PMID33980472
PMCPMC9099249
OpenAlexW3148433525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.