Evidence map›Paper›PMID 33980310›Full record

ArticleVeterinary research2021

Early response of monocyte-derived macrophages from vaccinated and non-vaccinated goats against in vitro infection with Mycobacterium avium subsp. paratuberculosis.

Noive Arteche-Villasol, Daniel Gutiérrez-Expósito, Raquel Vallejo, Jose Espinosa, Natalia Elguezabal, Iraia Ladero-Auñon, Marcos Royo, María Del Carmen Ferreras, Julio Benavides, Valentín Pérez

Open access · goldAbstract read
In one paragraph

Article in Veterinary research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Trained immunity in farm animals.Veterinary research · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Effects of SilirumAnimals : an open access journal from MDPI · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Noive Arteche-Villasol *Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad de León, Campus de Vegazana s/n, 24007, León, Spain. nartv@unileon.es.ORCID http://orcid.org/0000-0001-5793-9578
Daniel Gutiérrez-Expósito *Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad de León, Campus de Vegazana s/n, 24007, León, Spain.
Raquel VallejoDepartamento de Sanidad Animal, Facultad de Veterinaria, Universidad de León, Campus de Vegazana s/n, 24007, León, Spain.
Jose EspinosaDepartamento de Sanidad Animal, Facultad de Veterinaria, Universidad de León, Campus de Vegazana s/n, 24007, León, Spain.
Natalia ElguezabalDepartamento de Sanidad Animal, NEIKER-Instituto Vasco de Investigación y Desarrollo Agrario, Berreaga 1, Derio, 48169, Bizkaia, Spain.
Iraia Ladero-AuñonDepartamento de Sanidad Animal, NEIKER-Instituto Vasco de Investigación y Desarrollo Agrario, Berreaga 1, Derio, 48169, Bizkaia, Spain.
Marcos RoyoDepartamento de Sanidad Animal, Facultad de Veterinaria, Universidad de León, Campus de Vegazana s/n, 24007, León, Spain.
María Del Carmen FerrerasDepartamento de Sanidad Animal, Facultad de Veterinaria, Universidad de León, Campus de Vegazana s/n, 24007, León, Spain.
Julio BenavidesInstituto de Ganadería de Montaña (CSIC-ULE),, Finca Marzanas-Grulleros, 24346, León, Spain.
Valentín PérezDepartamento de Sanidad Animal, Facultad de Veterinaria, Universidad de León, Campus de Vegazana s/n, 24007, León, Spain.
Universidad de León · ESEuskadiko Parke Teknologikoa · ESInstituto de Ganadería de Montaña · ES

Funding

Junta de Castilla y León LE259P18Ministerio de Ciencia, Innovación y Universidades AGL2015-66540-C2-1-RMinisterio de Ciencia, Innovación y Universidades BES-2016-076513Ministerio de Ciencia, Innovación y Universidades FJC2019-042422-IMinisterio de Ciencia, Innovación y Universidades FJCI-2017-32020
6 · The paper itself

Abstract

Paratuberculosis is a disease of ruminants caused by Mycobacterium avium subsp. paratuberculosis (Map). Vaccination is the most cost-effective control method. However, despite the fact that macrophages are the main target cells for this pathogen, the precise mechanisms behind the response of the macrophage to Map infection and how it is modified by vaccination are yet poorly understood. The aim of this study was to investigate the effect of Silirum

Indexed as

AnimalsBacterial VaccinesGoat DiseasesGoatsLeukocytes, MononuclearMacrophagesMycobacterium avium subsp. paratuberculosisParatuberculosisVaccinationBacterial VaccinesCaprine monocyte-derived macrophagesMapPhagocytosisVaccinationViability

Identifiers

PMID33980310
PMCPMC8117269
OpenAlexW3161237001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.