ArticleMaternal health, neonatology and perinatology2021
The risk of diabetes after giving birth to a macrosomic infant: data from the NHANES cohort.
Article in Maternal health, neonatology and perinatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Global evidence on risk factors for the progression of gestational diabetes to type 2 diabetes: an umbrella review of systematic reviews and meta-analyses.Diabetology & metabolic syndrome · 2026Review
- Feeding the hospitalized large-for-gestational-age infant: Clinical dilemmas and the need for growth standards.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026Review
- First-trimester preexisting diabetes screening in Medicaid beneficiaries.Pregnancy (Hoboken, N.J.) · 2026Article
- Prevalence and determinants of macrosomia in low- and middle-income countries: a multilevel analysis of population survey data from 44 nations.Maternal health, neonatology and perinatology · 2025Article
- Prospective transitions in hemoglobin A1c following gestational diabetes using multistate Markov models.American journal of epidemiology · 2025Article
- History of large-for-gestational-age birth is independently associated with subsequent gestational diabetes in Chinese multiparous women: a retrospective cohort study.Frontiers in endocrinology · 2025Article
- Preconception HbA1c Levels in Adolescents and Young Adults and Adverse Birth Outcomes.JAMA network open · 2024Article
- Risk factors and diagnostic performance of predictors as a screening technique for gestational diabetes mellitus: a retrospective cross-sectional study.Annals of medicine and surgery (2012) · 2024Article
- Adverse pregnancy outcomes and risk of type 2 diabetes in postmenopausal women.American journal of obstetrics and gynecology · 2024Article
- Article
- Analysis of the Incidence of Macrosomia in Japan by Parental Nationalities at 5-year Intervals From 1995 to 2020.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2023Article
- A Brazilian cohort of pregnant women with overt diabetes: analyses of risk factors using a machine learning technique.Archives of endocrinology and metabolism · 2023Article
- Gestational Diabetes Mellitus-Recent Literature Review.Journal of clinical medicine · 2022Review
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Abstract
aimsGestational diabetes (GDM) increases the risk of developing type 2 diabetes and thus warrants earlier and more frequent screening. Women who give birth to a macrosomic infant, as defined as a birthweight greater than 9 lbs. (or approximately 4000 g), are encouraged to also get early type 2 diabetes screening, as macrosomia may be a surrogate marker for GDM. This study investigates whether a macrosomic infant, as defined as 9lbs, apart from GDM, increases the risk for diabetes later in life.
methodsData on parous women from the National Health and Nutrition Examination Survey (NHANES) 2007-2016 were utilized. Rates of diabetes were compared in those with and without macrosomic infants in Rao-Scott's chi-square test. Multiple logistic regression was used to test the independent effect of macrosomia on type 2 diabetes controlling for the confounding covariates and adjusting for the complex sampling design. To investigate how onset time affects diabetes, we implemented Cox proportional hazard regressions on time to have diabetes.
resultsAmong 10,089 parous women, macrosomia significantly increased the risk of maternal diabetes later in life in the chi-square test and logistic regression. Independent of GDM, women who deliver a macrosomic infant have a 20% higher chance of developing diabetes compared to women who did not. The expected hazards of having type 2 diabetes is 1.66 times higher in a woman with macrosomic infant compared to counterparts.
conclusionsWomen who gave birth to a macrosomic infant in the absence of GDM should be offered earlier and more frequent screening for type 2 diabetes.
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