Evidence map›Paper›PMID 33980300›Full record

ArticleJournal of medical case reports2021

Ozone therapy as an alternative method for the treatment of diabetic foot ulcer: a case report.

Navid Faraji, Rasoul Goli, Babak Choobianzali, Soheyla Bahrami, Ali Sadeghian, Nazila Sepehrnia, Mahmoodreza Ghalandari

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
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  5. Exploring the Potential of HCurrent pharmaceutical design · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Ozone therapy in musculoskeletal medicine: a comprehensive review.European journal of medical research · 2024
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Use of Ozone Therapy in Diabetic Foot Ulcers.Journal of personalized medicine · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Navid FarajiDepartment of Medical-Surgical Nursing, Nursing and Midwifery Faculty, School of Nursing and Midwifery, Urmia University of Medical Sciences, Campus Nazlu, 11 KM Road Seru, 575611-5111, Urmia, West Azerbaijan, Iran.
Rasoul GoliDepartment of Medical-Surgical Nursing, Nursing and Midwifery Faculty, School of Nursing and Midwifery, Urmia University of Medical Sciences, Campus Nazlu, 11 KM Road Seru, 575611-5111, Urmia, West Azerbaijan, Iran. Rasoulgoli94@gmail.com.ORCID http://orcid.org/0000-0001-7843-0084
Babak ChoobianzaliDepartment of Emergency Medicine, Medicine Faculty, Urmia University of Medical Sciences, Campus Nazlu, 11 KM Road Seru, 575611-5111, Urmia, West Azerbaijan, Iran.
Soheyla BahramiDepartment of Medical-Surgical Nursing, Nursing and Midwifery Faculty, School of Nursing and Midwifery, Islamic Azad University of BonaB Branch, Velayat Highway, 555178-5176, Bonab, East Azerbaijan, Iran.
Ali SadeghianDepartment of Medical-Surgical Nursing, School of Nursing and Midwifery, Zanjan University of Medical Sciences, Dr.Sobouti Blvd., 451395-6111, Zanjan, Iran.
Nazila SepehrniaDepartment of Psychiatric Nursing, Nursing and Midwifery Faculty, School of Nursing and Midwifery, Tabriz University of Medical Sciences, Shahnaz Street, 575611-5111, Tabriz, East Azerbaijan, Iran.
Mahmoodreza GhalandariDepartment of Medical-Surgical Nursing, Nursing and Midwifery Faculty, School of Nursing and Midwifery, Urmia University of Medical Sciences, Campus Nazlu, 11 KM Road Seru, 575611-5111, Urmia, West Azerbaijan, Iran.
Urmia University · IRIranshahr University · IRIran University of Medical Sciences · IRTabriz University of Medical Sciences · IRZanjan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetic foot ulcer (DFU) is one of the most important complications of diabetes that can lead to amputation. Treatment of DFUs is a major challenge and places a heavy economic and social burden on patients and their families. CASE PRESENTATION: The present case report is of a 52-year-old kurdish male patient with a 7-year history of type 2 diabetes. While on a bike ride, he sustained a traumatic injury to his right leg, which caused a deep gash measuring 14 × 5 cm on the tibia. During the hospital stay, no improvement was observed after routine wound care including suturing, antibiotic therapy, and dressing change. The patient was referred to our wound-care team. In the first step, the necrotic tissues of his foot ulcer were irrigated and then debrided using mechanical debridement and saline. Next, the patient underwent a 70 μg/dL dose of ozone therapy over a 30-day period in 10 sessions (one 20-minute session every 3 days). Between each session, the patient's wound was wrapped in silver-containing gauze bandages. After 1 month of wound-care using ozone therapy, the patient's foot ulcer had healed and he was discharged from our wound-care service with a stable and good general condition.

conclusionConsidering the effectiveness of ozone therapy along with silver-containing dressing in the treatment of DFUs, wound-care teams can utilize it as an adjunct to the standard methods of DFU treatment.

Indexed as

Diabetes Mellitus, Type 2Diabetic FootOzoneBandagesHumansMaleMiddle AgedWound HealingOzoneDiabetic footInfectionOzoneSilverWound

Identifiers

PMID33980300
PMCPMC8117654
OpenAlexW3160670236

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.