Evidence map›Paper›PMID 33980226›Full record

Observational studyRespiratory research2021

Characteristics and treatable traits of patients with chronic obstructive pulmonary disease (COPD) with and without paid employment.

Peter A Jacobsen, Alex J van 't Hul, Remco S Djamin, Jeanine C Antons, Marianne de Man, Ulla Møller Weinreich, Martijn A Spruit, Daisy J A Janssen

Abstract readComparative StudyObservational Study
In one paragraph

Observational study in Respiratory research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Employment Status, Readmission and Mortality After Acute Exacerbation of COPD.International journal of chronic obstructive pulmonary disease · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Peter A JacobsenDepartment of Respiratory Diseases, Aalborg University Hospital, Mølleparkvej 4, 9100, Aalborg, Denmark. peter.jacobsen@rn.dk.ORCID http://orcid.org/0000-0001-6083-7441
Alex J van 't HulDepartment of Respiratory Diseases, Radboud University Medical Center, Radboud Institute for Health Sciences, 6525 GA, Nijmegen, The Netherlands.
Remco S DjaminDepartment of Respiratory Diseases, Amphia Hospital, 4818 CK, Breda, The Netherlands.
Jeanine C AntonsDepartment of Respiratory Diseases, Radboud University Medical Center, Radboud Institute for Health Sciences, 6525 GA, Nijmegen, The Netherlands.
Marianne de ManDepartment of Respiratory Diseases, 5406, Uden, The Netherlands.
Ulla Møller WeinreichDepartment of Respiratory Diseases, Aalborg University Hospital, Mølleparkvej 4, 9100, Aalborg, Denmark.
Martijn A SpruitDepartment of Research and Development, Ciro, Horn, The Netherlands.
Daisy J A JanssenDepartment of Research and Development, Ciro, Horn, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatients with COPD are vulnerable to workforce detachment. Better knowledge of features associated with paid work loss might be of help to design and select appropriate interventions.

methodThis cross-sectional study aimed to explore the presence of treatable traits in COPD patients without paid work. Patients with COPD below 65 years at first referral to a hospital-based patient clinic were included. Using binary logistic regression analysis, the relationship between paid work and the following characteristics was explored: low daily physical activity, exercise, active smoking, Medical Research Council dyspnea scale (MRC), poor nutritional status, exacerbations, and fatigue (checklist individual strength (CIS)). Variables were adjusted for age, sex, forced expiratory volume in 1 s (FEV 1), and education level.

resultsIn total, 191 patients (47.3%) were without paid work. The following treatable traits were related to not being in paid work: < 5000 steps/day (OR 2.36, 95% CI (1.52-3.68)), MRC ≥ 3 (OR 1.78, 95%CI (1.14-2.77)), CIS ≥ 36 points (OR 1.78, 95% CI (1.10-2.87)), six-minute walk distance (6MWD) < 70% of predicted (OR 2.62, 95% CI (1.69-4.06)), and ≥ 2 exacerbations per year (OR 1.80, 95% CI (1.12-2.92)). Significant differences were also seen in age (OR 1.06, 95% CI (1.02-1.10) per year), FEV 1% predicted (OR 0.98, 95% CI (0.97-1.00) per % predicted increase), and medium/high education level (OR 0.62, 95% CI (0.41-0.93)). When adjusting for all variables the only treatable trait that remained significant was 6MWD.

conclusionPatients without paid work are more likely to have treatable traits with 6MWD revealing the most significant association.

Indexed as

EmploymentExercise ToleranceSalaries and Fringe BenefitsAgedCross-Sectional StudiesFemaleForced Expiratory VolumeHumansLungMaleMiddle AgedMuscle StrengthNetherlandsNutritional StatusNutrition AssessmentPhenotypeChronic Obstructive Pulmonary Disease (COPD)OccupationWorkforce connection

Identifiers

PMID33980226
PMCPMC8117298

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.