ArticleBMC cardiovascular disorders2021
Echocardiographic left ventricular geometry profiles for prediction of stroke, coronary heart disease and all-cause mortality in the Chinese community: a rural cohort population study.
Article in BMC cardiovascular disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 25 citations in OpenAlex.
- Cardiac magnetic resonance assessment of left ventricular phenotypes and prognostic implications in hypertensive heart disease.Clinical hypertension · 2026Article
- Automated ejection fraction and risk stratification in cardiomyopathy patients with diverse LV geometry using 2D echocardiography.Scientific reports · 2025Article
- Cardiac CT in Large Vessel Occlusion Stroke for the Evaluation of Non-Thrombotic and Non-Atrial-Fibrillation-Related Embolic Causes.Neurology international · 2025Article
- Analysis of temporal and spatial changes in the global burden of hypertensive heart disease based on data from the Global Burden of Disease study database and future projections: 1990-2046.Frontiers in cardiovascular medicine · 2025Article
- Assessment of Left Ventricular Shape Index and Eccentricity Index as Promising Parameters for Detection of Left Ventricular Remodeling in Cardiovascular Events.Current cardiology reviews · 2025Review
- New-onset aortic dilatation in the population: a quarter-century follow-up.Clinical research in cardiology : official journal of the German Cardiac Society · 2023Article
- Cardiac Morphology, Function, and Left Ventricular Geometric Pattern in Patients with Hypertensive Crisis: A Cardiovascular Magnetic Resonance-Based Study.Journal of cardiovascular development and disease · 2023Article
- Plasma Proteomic Patterns Show Sex Differences in Early Concentric Left Ventricular Remodeling.Circulation. Heart failure · 2023Article
- Association of Abnormal Serum L-Carnitine Levels with Idiopathic Changes in Left Ventricular Geometry in Pediatric and Adolescent Patients.Iranian journal of medical sciences · 2022Article
- Diagnostic utility of 31 ECG criteria for predicting echocardiographic left ventricular geometry.Archivos de cardiologia de Mexico · 2022Article
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5 authors at 2 institutions in 1 country.
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Abstract
backgroundThe utility of echocardiographic left ventricular (LV) geometry in the prediction of stroke/coronary heart disease (CHD) and all-cause mortality is not well characterized. This study aimed to evaluate the overall and sex-specific prognostic value of different geometric patterns on the incidence of stroke/CHD and all-cause mortality in a Chinese population-based cohort.
methodsWe conducted a prospective study in the general population in Northeast China, and a total of 9940 participants aged ≥ 35 years underwent echocardiography for LV geometry and were successfully followed up for incident stroke/CHD and all-cause death. Cox proportional hazards models were utilized to estimate the association of baseline LV geometry with adverse outcomes.
resultsOver a median follow-up of 4.66 years, abnormal LV geometric patterns had increased crude incident rates of stroke/CHD and all-cause mortality compared with normal geometry in overall population and each sex group (all P < 0.05). Multivariable Cox analysis reported that LV concentric and eccentric hypertrophy were associated with incident stroke/CHD (concentric hypertrophy: hazard ratio (HR) = 1.39, 95% confidence interval (CI) = 1.04-1.86; eccentric hypertrophy: HR = 1.42, 95% CI = 1.11-1.82) and all-cause mortality (concentric hypertrophy: HR = 1.50, 95% CI = 1.07-2.12; eccentric hypertrophy: HR = 1.58, 95% CI = 1.19-2.10), and LV concentric remodeling was related to stroke/CHD incidence (HR = 1.42, 95% CI = 1.09-1.84) in total population compared to normal geometry after the adjustment for potential confounders. In men, a significant increase was observed from LV eccentric hypertrophy for incident stroke/CHD, whereas in women, LV concentric hypertrophy was associated with elevated incidence of both stroke/CHD and all-cause death, and eccentric hypertrophy was correlated with increased all-cause mortality (all P < 0.05).
conclusionsOur prospective cohort supports that abnormal LV geometry by echocardiography has a prognostic significance for incident stroke/CHD and all-cause mortality, implying that early detection and intervention of LV structural remodeling in rural China are urgently needed to prevent adverse outcomes.
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