Evidence map›Paper›PMID 33979965›Full record

ArticleZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology2021

[Methylene blue play a role in preventing septic liver injury by inducing macrophage polarization].

H Li, L J Tian, Z L Bian, Q Chen, L L Shi, X D Han

Abstract read
In one paragraph

Article in Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. [Effects of in vivo targeted carboxylesterase 1f gene knockdown on the Kupffer cells polarization activity in mice with acute liver failure].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

H LiMedical School of Nantong University, Nantong 226001, China Intensive Care Unit, Nantong Third People's Hospital, Nantong 226000, China.
L J TianIntensive Care Unit, Nantong Third People's Hospital, Nantong 226000, China.
Z L BianDepartment of Gastroenterology, Nantong Third People's Hospital, Nantong 226000, China.
Q ChenMedical School of Nantong University, Nantong 226001, China.
L L ShiMedical School of Nantong University, Nantong 226001, China.
X D HanIntensive Care Unit, Nantong Third People's Hospital, Nantong 226000, China.

Funding

Science and Technology Program of Nantong JC2020054, MS12018040, MS22018007The Scientific Research Project of Nantong Health Commission QA2019033, MA2020017The support Project of Nantong Key Discipline wx2017002
6 · The paper itself

Abstract

Thirty mice were used to establish a sepsis model with cecal ligation and puncture. 15 mg/kg methylene blue or isotonic saline were injected intraperitoneally to observe liver tissue pathological changes. Changes in macrophage frequency and expressional condition of M1 and M2-type hepatic inflammatory factors were detected. After LPS stimulation, the expression level of macrophage inflammatory factor were detected. The results showed that the pathological liver injury was significantly reduced in the MB mice group (

Indexed as

Macrophage ActivationMethylene BlueAnimalsLiverMacrophagesMiceMice, Inbred C57BLMethylene BlueLiver injuryMacrophageMethylene blueSepsis

Identifiers

PMID33979965
PMCPMC12813808

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.