Evidence map›Paper›PMID 33979626›Full record

ArticleCell reports2021

Resident memory T cells in tumor-distant tissues fortify against metastasis formation.

Laura S Christian, Liuyang Wang, Bryan Lim, Dachuan Deng, Haiyang Wu, Xiao-Fan Wang, Qi-Jing Li

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Tissue-resident memory T cells reshapeFrontiers in immunology · 2026
    Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Aberrant CD8Frontiers in immunology · 2024
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Laura S ChristianDepartment of Immunology, Duke University Medical Center, Durham, NC 27710, USA.
Liuyang WangDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.
Bryan LimDepartment of Immunology, Duke University Medical Center, Durham, NC 27710, USA.
Dachuan DengTCRCure (TianKeYa) Biopharma, Ltd., Durham, NC 27701, USA.
Haiyang WuTCRCure (TianKeYa) Biopharma, Ltd., Durham, NC 27701, USA.
Xiao-Fan WangDepartments of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.
Qi-Jing LiDepartment of Immunology, Duke University Medical Center, Durham, NC 27710, USA. Electronic address: qi-jing.li@duke.edu.
Duke University Hospital · USDuke Medical Center · US

Funding

Project 3: Phase-2 Trial of Oncolytic Poliovirus (PVSRIPO) combined with CCNU (lomustine) against Recurrent GlioblastomaP01CA225622 · NCI · DUKE UNIVERSITY · PI WEINHOLD, KENT J. · 2018 to 2022
$12.2M
Basic Immunology Training ProgramT32AI052077 · NIAID · DUKE UNIVERSITY · PI KRANGEL, MICHAEL S · 2002 to 2024
$4.2M
NGF recruits nerve fibers to reprogram an immunosuppressive microenvironment in melanomaR01CA249726 · NCI · DUKE UNIVERSITY · PI WANG, XIAO-FAN · 2020 to 2024
$2.4M
Targeting UHRF1 in combinational immunotherapyR01CA233205 · NCI · DUKE UNIVERSITY · PI WANG, XIAO-FAN · 2019 to 2023
$2.3M
Area A: Development of genetically tractable, driver gene-syngeneic brain tumor models for pre-clinical adoptive TCR-T therapyR33CA225328 · NCI · DUKE UNIVERSITY · PI ASHLEY, DAVID M., LI, QIJING · 2017 to 2017
$1.5M
NCI NIH HHS P01 CA225622NCI NIH HHS R01 CA233205NCI NIH HHS R01 CA249726NCI NIH HHS R33 CA225328NIAID NIH HHS T32 AI052077
6 · The paper itself

Abstract

As a critical machinery for rapid pathogen removal, resident memory T cells (T

Indexed as

AnimalsHumansMemory T CellsMiceNeoplasm MetastasisNeoplasmsTransfectionbreast cancermetastasisontogenyresident memory T cellssingle-cell RNA sequencingTCR-β repertoire sequencingtumor immunology

Identifiers

PMID33979626
PMCPMC8204287
OpenAlexW3163204015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.