Evidence map›Paper›PMID 33979548›Full record

ArticleTissue engineering. Part A2021

Extracellular Matrix Alignment Directs Provisional Matrix Assembly and Three Dimensional Fibrous Tissue Closure.

Shoshana L Das, Prasenjit Bose, Emma Lejeune, Daniel H Reich, Christopher Chen, Jeroen Eyckmans

Open access · greenAbstract read
In one paragraph

Article in Tissue engineering. Part A, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Shoshana L DasHarvard-MIT Program in Health Sciences and Technology, Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Prasenjit BoseDepartment of Physics and Astronomy, Johns Hopkins University, Baltimore, Maryland, USA.
Emma LejeuneDepartment of Mechanical Engineering, Boston University, Boston, Massachusetts, USA.
Daniel H ReichDepartment of Physics and Astronomy, Johns Hopkins University, Baltimore, Maryland, USA.
Christopher ChenDepartment of Biomedical Engineering, Boston University, Boston, Massachusetts, USA.
Jeroen EyckmansDepartment of Biomedical Engineering, Boston University, Boston, Massachusetts, USA.
Boston University · USJohns Hopkins University · US

Funding

Development of a wound-on-chip model to study stromal-epithelial interactions during tissue repairR21EB028491 · NIBIB · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI EYCKMANS, JEROEN · 2020 to 2022
$660k
NIBIB NIH HHS R21 EB028491
6 · The paper itself

Abstract

Gap closure is a dynamic process in wound healing, in which a wound contracts and a provisional matrix is laid down, to restore structural integrity to injured tissues. The efficiency of wound closure has been found to depend on the shape of a wound, and this shape dependence has been echoed in various

Indexed as

Extracellular MatrixFibronectinsFibroblastsWound HealingFibronectinsECM alignmentfibronectinprovisional matrix assemblytissue repairwound closure

Identifiers

PMID33979548
PMCPMC8742281
OpenAlexW3138738665

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.