ReviewJournal of neuropsychology2022
Neural basis of affective touch and pain: A novel model suggests possible targets for pain amelioration.
Review in Journal of neuropsychology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Touch-based interventions, biofield therapies, and hypnosis for pain management: a scoping review of complementary approaches in physiotherapy.Frontiers in pain research (Lausanne, Switzerland) · 2026Pooled it
- Guideline
- Application of Affective Touch in Patients With Advanced Cancer: Effects on Existential Distress, Pain, and Quality of Life.The journal of nursing research : JNR · 2026Trial
- Penetrating spinal cord injury transiently inhibits responsiveness to touch in mice.IBRO neuroscience reports · 2026Article
- The hijacked insula: A stratified model of affective touch modulation in chronic pain.Journal of neuropsychology · 2026Review
- Affective-touch experiences and interpersonal space in anorexia nervosa.Eating and weight disorders : EWD · 2026Article
- Modulation of pain by affective touch: effects of childhood trauma, depression, chronic pain, and spinal segment.The Journal of physiology · 2026Article
- MASSAG model: Towards an integrative neuroscience framework linking emotional trauma, pain, and mechanisms of force-based manipulations.Neuroscience and biobehavioral reviews · 2026Review
- Affective tactile stimulation ameliorates chronic pain and comorbid anxiety by modulating hippocampal CA1 oscillations and functional connectivity.Frontiers in molecular neuroscience · 2026Article
- Effectiveness of virtual reality-based exercise rehabilitation for enhancing functional outcomes and quality of life in adult cancer survivors: A systematic review of randomized controlled trials.Journal of cancer survivorship : research and practice · 2025Review
- Pain integration of multimodal noxious stimulation based on the perceptual instruction.Proceedings. Biological sciences · 2025Article
- Neural responses to social touch with different emotional valences: an fNIRS study.Social cognitive and affective neuroscience · 2025Article
- Does affective touch buffer emotional distress? Insights from subjective and physiological indices.Social cognitive and affective neuroscience · 2025Article
- Linking heartbeats with the cortical network dynamics involved in self-social touch distinction.Communications biology · 2025Article
- The Hedonic Experience Associated with a Gentle Touch Is Preserved in Women with Fibromyalgia.Journal of clinical medicine · 2024Article
- Review
- A modern way to teach and practice manual therapy.Chiropractic & manual therapies · 2024Review
- Tactile, Auditory, and Visual Stimulation as Sensory Enrichment for Dairy Cattle.Animals : an open access journal from MDPI · 2024Review
- Spatial factors influencing the pain-ameliorating effect of CT-optimal touch: a comparative study for modulating temporal summation of second pain.Scientific reports · 2024Article
- CT-optimal touch and chronic pain experience in Parkinson's Disease; An intervention study.PloS one · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pain is one of the most common health problems and has a severe impact on quality of life. Yet, a suitable and efficient treatment is still not available for all patient populations suffering from pain. Interestingly, recent research shows that low threshold mechanosensory C-tactile (CT) fibres have a modulatory influence on pain. CT-fibres are activated by slow gentle stroking of the hairy skin, providing a pleasant sensation. Consequently, slow gentle stroking is known as affective touch. Currently, a clear overview of the way affective touch modulates pain, at a neural level, is missing. This review aims to present such an overview. To explain the interaction between affective touch and pain, first the neural basis of the affective touch system and the neural processing of pain will be described. To clarify these systems, a schematic illustration will be provided in every section. Hereafter, a novel model of interactions between affective touch and pain systems will be introduced. Finally, since affective touch might be suitable as a new treatment for chronic pain, possible clinical implications will be discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.