Evidence map›Paper›PMID 33979132›Full record

ArticleInorganic chemistry2021

Piano-Stool Ruthenium(II) Complexes with Delayed Cytotoxic Activity: Origin of the Lag Time.

Laia Rafols, Dana Josa, David Aguilà, Leoní A Barrios, Olivier Roubeau, Jordi Cirera, Vanessa Soto-Cerrato, Ricardo Pérez-Tomás, Manuel Martínez, Arnald Grabulosa and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Inorganic chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 30 citations in OpenAlex.

  1. Graph neural networks for predicting metal-ligand coordination of transition metal complexes.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Synthesis, characterization, and biological activity of cationic ruthenium-arene complexes with sulfur ligands.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2024
    Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Laia RafolsDepartament de Química Inorgànica i Orgànica, Facultat de Química, Secció de Química Inorgànica, Universitat de Barcelona, Martí i Franquès, 1-11, 08028 Barcelona, Spain.ORCID http://orcid.org/0000-0002-2159-9636
Dana JosaDepartament de Química Inorgànica i Orgànica, Facultat de Química, Secció de Química Inorgànica, Universitat de Barcelona, Martí i Franquès, 1-11, 08028 Barcelona, Spain.ORCID http://orcid.org/0000-0003-0870-3432
David AguilàDepartament de Química Inorgànica i Orgànica, Facultat de Química, Secció de Química Inorgànica, Universitat de Barcelona, Martí i Franquès, 1-11, 08028 Barcelona, Spain.ORCID http://orcid.org/0000-0001-8707-7833
Leoní A BarriosDepartament de Química Inorgànica i Orgànica, Facultat de Química, Secció de Química Inorgànica, Universitat de Barcelona, Martí i Franquès, 1-11, 08028 Barcelona, Spain.
Olivier RoubeauInstituto de Ciencia de Materiales de Aragón (ICMA), CSIC and Universidad de Zaragoza, Pedro Cerbuna 12, 50009 Zaragoza, Spain.ORCID http://orcid.org/0000-0003-2095-5843
Jordi CireraDepartament de Química Inorgànica i Orgànica, Facultat de Química, Secció de Química Inorgànica, Universitat de Barcelona, Martí i Franquès, 1-11, 08028 Barcelona, Spain.
Vanessa Soto-CerratoDepartment of Pathology and Experimental Therapeutics, Faculty of Medicine and Health Sciences, University of Barcelona, Campus Bellvitge, Feixa Llarga s/n, 08907 L'Hospitalet de Llobregat (Barcelona), Spain.
Ricardo Pérez-TomásDepartment of Pathology and Experimental Therapeutics, Faculty of Medicine and Health Sciences, University of Barcelona, Campus Bellvitge, Feixa Llarga s/n, 08907 L'Hospitalet de Llobregat (Barcelona), Spain.
Manuel MartínezDepartament de Química Inorgànica i Orgànica, Facultat de Química, Secció de Química Inorgànica, Universitat de Barcelona, Martí i Franquès, 1-11, 08028 Barcelona, Spain.ORCID http://orcid.org/0000-0002-6289-4586
Arnald GrabulosaDepartament de Química Inorgànica i Orgànica, Facultat de Química, Secció de Química Inorgànica, Universitat de Barcelona, Martí i Franquès, 1-11, 08028 Barcelona, Spain.ORCID http://orcid.org/0000-0003-0198-4139
Patrick GamezDepartament de Química Inorgànica i Orgànica, Facultat de Química, Secció de Química Inorgànica, Universitat de Barcelona, Martí i Franquès, 1-11, 08028 Barcelona, Spain.ORCID http://orcid.org/0000-0003-2602-9525
Institut de Nanociència i Nanotecnologia de la Universitat de BarcelonaInstitut d'Investigació Biomédica de Bellvitge · ESUniversitat de Barcelona · ESInstitució Catalana de Recerca i Estudis Avançats · ESUniversidad de Zaragoza · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have recently reported a series of piano-stool ruthenium(II) complexes of the general formula [RuCl

Indexed as

Antineoplastic AgentsCell ProliferationCell SurvivalCoordination ComplexesCrystallography, X-RayDose-Response Relationship, DrugDrug Screening Assays, AntitumorHumansModels, MolecularMolecular ConformationRutheniumTime FactorsTumor Cells, CulturedAntineoplastic AgentsCoordination ComplexesRuthenium

Identifiers

PMID33979132
PMCPMC8659375
OpenAlexW3161147259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.