ArticleCancer medicine2021
Decreasing trends in thyroid cancer incidence in South Korea: What happened in South Korea?
Article in Cancer medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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30 citing papers in PubMed, 44 citations in OpenAlex.
- [Ecological analysis of the association between dietary factors and thyroid carcinoma incidence based on GBD 2021 data].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2026Article
- Article
- Cancer incidence near nuclear facilities in Korea (2005-2022): implications of regional socioeconomic status and industrial context.BMC public health · 2026Article
- Impact of UGT1A9 Expression on Analgesic Efficacy and Safety of Postoperative Ketorolac in Thyroid Cancer Surgery: A Prospective Cohort Study.Journal of pain research · 2026Article
- Global, regional, and national burden of thyroid cancer in working-age population: A systematic analysis for the Global Burden of Disease Study 2021.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2025Article
- Clinical Outcomes of Follicular Thyroid Carcinoma Did Not Significantly Differ according to Tumor Size in an Iodine-Excessive Country.Endocrinology and metabolism (Seoul, Korea) · 2025Article
- Clarifying the misinterpretation of case-fatality rate as mortality in thyroid cancer studies.International journal of surgery (London, England) · 2025Article
- FTOZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Article
- Review
- Thyroid cancer survival and prognostic factors in Yantai, China (2012-2022): a population-based study.BMC cancer · 2024Article
- Decreasing trend in thyroid cancer incidence: a study from central Italy (2007-2019).Endocrine · 2024Article
- The growing global burden of thyroid cancer overdiagnosis.The lancet. Diabetes & endocrinology · 2024Article
- The association between BMI and BRAFV600E mutation may differ by primary tumor size.European thyroid journal · 2024Article
- Prevalence of thyroid nodule and relationship with physiological and psychosocial factors among adults in Zhejiang Province, China: a baseline survey of a cohort study.BMC public health · 2024Article
- Contents analysis of thyroid cancer-related information uploaded to YouTube by physicians in Korea: endorsing thyroid cancer screening, potentially leading to overdiagnosis.BMC public health · 2024Article
- Article
- Long-Term Changes in the Mortality Rates of Thyroid Cancer in Korea: Analysis of Korean National Data from 1985 to 2020.Endocrinology and metabolism (Seoul, Korea) · 2023Article
- Cancer incidence and type of treatment hospital among children, adolescents, and young adults in Japan, 2016-2018.Cancer science · 2023Article
- Gastroesophageal reflux disease and risk of cancer: Findings from the Korean National Health Screening Cohort.Cancer medicine · 2023Article
- Linear association between radioactive iodine dose and second primary malignancy risk in thyroid cancer.Journal of the National Cancer Institute · 2023Article
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSouth Korea has the highest incidence of thyroid cancer in the world. Our study examined the trends in thyroid cancer incidence by the histologic type, cancer stage, and age group and explored possible factors that affected thyroid cancer trends.
methodsWe conducted a descriptive epidemiological study using the national cancer registry data and cause of death data from 1999 to 2016 in South Korea. Age-standardized rates were calculated using Segi's world standard population. Joinpoint regression analysis was applied to determine the changing point of thyroid cancer trends according to histologic type; Surveillance, Epidemiology, and End Results (SEER) summary stage; and age groups by sex.
resultsThe age-standardized incidence of thyroid cancer in both men and women increased from 6.3 per 100,000 people in 1999 to 63.4 per 100,000 in 2012 but declined from 2012 to 2016, before the debates for over diagnosis of thyroid cancer began in 2014. The age-standardized mortality rate of thyroid cancer, incidence of distant thyroid cancer, and incidence of regional and localized thyroid cancer started to decline since early 2000, 2010, and 2012, respectively. In addition, thyroid cancer prevalence in thyroid nodules showed decreasing trends from 1999-2000 to 2013-2014.
conclusionsThe incidence of thyroid cancer began declining from 2012, before the debates for over diagnosis of thyroid cancer began in 2014. Changes in guidelines for thyroid nodule examinations may have affected this inflection point. Moreover, the debates for over diagnosis of thyroid cancer may have accelerated the decline in thyroid cancer.
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