Evidence map›Paper›PMID 33978904›Full record

ArticleJournal of neurovirology2021

Progressive multifocal leukoencephalopathy and Creutzfeldt-Jakob disease: population-wide incidences, comorbidities, costs of care, and outcomes.

J A Bakal, C L Charlton, B Hlavay, G H Jansen, L W Svenson, C Power

Abstract read
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In one paragraph

Article in Journal of neurovirology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

J A BakalProvincial Research Data Services-Alberta Health Services, Edmonton, AB, Canada.
C L CharltonPublic Health Laboratory, Alberta Precision Laboratories, Edmonton, AB, Canada.
B HlavayDepartment of Medicine, Medical Research Centre, University of Alberta, 6-11 Heritage, Edmonton, AB, Canada.
G H JansenDivision of Anatomical Pathology, University of Ottawa, Ottawa, ON, Canada.
L W SvensonDepartment of Medicine, Medical Research Centre, University of Alberta, 6-11 Heritage, Edmonton, AB, Canada.
C PowerDepartment of Medicine, Medical Research Centre, University of Alberta, 6-11 Heritage, Edmonton, AB, Canada. chris.power@ualberta.ca.ORCID 0000-0002-5131-9711
University of Alberta · CAAlberta Health Services · CAHeritage Foundation · USUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurological disorders associated with chronic infections are often progressive as well as challenging to diagnose and manage. Among 4.4 million persons from 2004 to 2019 receiving universal health, progressive multifocal leukoencephalopathy (PML, n = 58) and Creutzfeldt-Jakob disease (CJD, n = 93) cases were identified, revealing stable yearly incidence rates with divergent comorbidities: HIV/AIDS affected 37.8% of PML cases while cerebrovascular disease affected 26.9% of CJD cases. Most CJD cases died within 1 year (73%) although PML cases lived beyond 5 years (34.1%) despite higher initial costs of care. PML and CJD represent important neurological disorders with evolving risk variables and impact on health care.

Indexed as

Cost of IllnessAdultAgedAged, 80 and overAlbertaCerebrovascular DisordersChronic DiseaseComorbidityCreutzfeldt-Jakob SyndromeFemaleHIV InfectionsHumansIncidenceLeukoencephalopathy, Progressive MultifocalMaleMiddle AgedComorbiditiesCosts of careCreutzfeldt-Jakob diseaseOutcomesPopulation epidemiologyProgressive multifocal leukoencephalopathy

Identifiers

PMID33978904
OpenAlexW3162489425

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.