Evidence map›Paper›PMID 33978901›Full record

ArticleMetabolic brain disease2021

Combination of donepezil and gallic acid improves antioxidant status and cholinesterases activity in aluminum chloride-induced neurotoxicity in Wistar rats.

Tajudeen O Obafemi, Olutumise V Owolabi, Benjamin O Omiyale, Blessing A Afolabi, Oluwafemi A Ojo, Amos Onasanya, Isaac A I Adu, Damilare Rotimi

Abstract read
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In one paragraph

Article in Metabolic brain disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
6.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Tajudeen O ObafemiDepartment of Biochemistry, Afe Babalola University, PMB, Ado-Ekiti, 5454, Nigeria. oobafemi@abuad.edu.ng.ORCID http://orcid.org/0000-0001-8894-9365
Olutumise V OwolabiMedical Biochemistry Unit, College of Medicine and Health Sciences, Afe Babalola University, PMB, Ado-Ekiti, 5454, Nigeria.
Benjamin O OmiyaleMedical Biochemistry Unit, College of Medicine and Health Sciences, Afe Babalola University, PMB, Ado-Ekiti, 5454, Nigeria.
Blessing A AfolabiDepartment of Biochemistry, Bowen University, PMB 284, Iwo, Nigeria.
Oluwafemi A OjoDepartment of Biochemistry, Landmark University, PMB, Omu-aran, 1001, Nigeria.
Amos OnasanyaDepartment of Biochemistry, Afe Babalola University, PMB, Ado-Ekiti, 5454, Nigeria.
Isaac A I AduMedical Biochemistry Unit, College of Medicine and Health Sciences, Afe Babalola University, PMB, Ado-Ekiti, 5454, Nigeria.
Damilare RotimiDepartment of Biochemistry, Landmark University, PMB, Omu-aran, 1001, Nigeria.
Afe Babalola University · NGLandmark University · NGBowen University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study compared the effect of donepezil only and combination of donepezil and gallic acid on oxidative status and cholinesterase activity in the brain of Wistar rats administered AlCl

Indexed as

AntioxidantsGallic AcidAcetylcholinesteraseAluminum ChlorideAnimalsButyrylcholinesteraseDonepezilLipid PeroxidationOxidative StressRatsRats, WistarAcetylcholinesteraseAluminum ChlorideAntioxidantsButyrylcholinesteraseDonepezilGallic AcidAcetylcholinesteraseAluminium chlorideCatalaseDonepezilGallic acid

Identifiers

PMID33978901
OpenAlexW3160596412

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.