Evidence map›Paper›PMID 33978815›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2021

The impact of epicardial adipose tissue in patients with acute myocardial infarction.

Christoph Fisser, Stefan Colling, Kurt Debl, Andrea Hetzenecker, Ulrich Sterz, Okka W Hamer, Claudia Fellner, Lars S Maier, Stefan Buchner, Michael Arzt

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Epicardial Adipocytes in Cardiac Pathology and Healing.Cardiovascular drugs and therapy · 2025
    Review
  5. Article
  6. NSTEMI Risk Prediction with the Combination of the Biomarkers Epicardial Adipose Tissue and Soluble Suppression of Tumorigenicity 2.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Observational
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Epicardial Adipose Tissue in Patients with Coronary Artery Disease: A Meta-Analysis.Journal of cardiovascular development and disease · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Christoph Fisser *Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany. Christoph.Fisser@ukr.de.ORCID http://orcid.org/0000-0001-5833-1230
Stefan Colling *Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany.
Kurt DeblDepartment of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany.
Andrea HetzeneckerDepartment of Pneumology, Donaustauf Hospital, Donaustauf, Germany.
Ulrich SterzDepartment of Internal Medicine III, University Hospital Regensburg, Regensburg, Germany.
Okka W HamerInstitute for Radiology, University Hospital Regensburg, Regensburg, Germany.
Claudia FellnerInstitute for Radiology, University Hospital Regensburg, Regensburg, Germany.
Lars S MaierDepartment of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany.
Stefan Buchner *Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany.
Michael Arzt *Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany.
University Hospital Regensburg · DEKlinik Donaustauf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsEpicardial adipose tissue (EAT) has been linked to impaired reperfusion success after percutaneous coronary intervention (PCI). Whether EAT predicts myocardial damage in the early phase after acute myocardial infarction (MI) is unclear. Therefore, we investigated whether EAT in patients with acute MI is associated with more microvascular obstruction (MVO), greater ST-deviation, larger infarct size and reduced myocardial salvage index (MSI). METHODS AND

resultsThis retrospective analysis of a prospective observational study including patients with acute MI (n = 54) undergoing PCI and 12 healthy matched controls. EAT, infarct size and MSI were analyzed with cardiac magnetic resonance imaging, conducted 3-5 days and 12 weeks after MI. Patients with acute MI showed higher EAT volume than healthy controls (46 [25.;75. percentile: 37;59] vs. 24 [15;29] ml, p < 0.001). The high EAT group (above median) showed significantly more MVO (2.22 [0.00;5.38] vs. 0.0 [0.00;2.18] %, p = 0.004), greater ST-deviation (0.38 [0.22;0.55] vs. 0.15 [0.03;0.20] mV×10

conclusionsPatients with acute MI showed higher volume of EAT than healthy individuals. High EAT was linked to more MVO and greater ST-deviation. EAT was associated with infarct size, but not with MSI.

Indexed as

Adipose TissueAdultAgedCase-Control StudiesFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedMyocardial InfarctionPercutaneous Coronary InterventionPericardiumRetrospective StudiesAcute myocardial infarctionEpicardial adipose tissueInfarct sizeMicrovascular obstructionMyocardial salvage indexST-deviation

Identifiers

PMID33978815
PMCPMC8484200
OpenAlexW3160333077

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.