Evidence map›Paper›PMID 33978798›Full record

ReviewPediatric radiology2021

Contrast-enhanced ultrasound of pediatric lungs.

Vasileios Rafailidis, Savvas Andronikou, Hans-Joachim Mentzel, Maciej Piskunowicz, Judy H Squires, Carol E Barnewolt

Open access · hybridAbstract readReview
In one paragraph

Review in Pediatric radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
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  13. Review
  14. Overview of Lung Ultrasound in Pediatric Cardiology.Diagnostics (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 4 countries.

Vasileios RafailidisDepartment of Radiology, King's College Hospital, Denmark Hill, London, SE5 9RS, UK. billraf@hotmail.com.
Savvas AndronikouDepartment of Radiology, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Hans-Joachim MentzelSection of Pediatric Radiology, Institute of Diagnostic and Interventional Radiology, University Hospital, Jena, Germany.
Maciej PiskunowiczDepartment of Radiology, Medical University of Gdansk, Gdansk, Poland.
Judy H SquiresDepartment of Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Carol E BarnewoltDepartment of Radiology, Boston Children's Hospital, Harvard University, Boston, MA, USA.
Children's Hospital of Philadelphia · USGdańsk Medical University · PLHarvard University · USJena University Hospital · DEKing's College Hospital · GBUniversity of Pittsburgh Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In addition to radiography, ultrasound (US) has long proved to be a valuable imaging modality to evaluate the pediatric lung and pleural cavity. Its many inherent advantages, including real-time performance, high spatial resolution, lack of ionizing radiation and lack of need for sedation make it preferable over other imaging modalities such as CT. Since the introduction of ultrasound contrast agents (UCAs), contrast-enhanced ultrasound (CEUS) has become a valuable complementary US technique, with many well-established uses in adults and evolving uses in children. Lung CEUS applications are still not licensed and are performed off-label, although the added value of CEUS in certain clinical scenarios is increasingly reported. The limited evidence of CEUS in the evaluation of pediatric lungs focuses primarily on community-acquired pneumonia and its complications. In this clinical setting, CEUS is used to confidently and accurately diagnose necrotizing pneumonia and to delineate pleural effusions and empyema. In addition to intravenous use, UCAs can be administered directly into the pleural cavity through chest catheters to improve visualization of loculations within a complex pleural effusion, which might necessitate fibrinolytic therapy. The purpose of this paper is to present the current experience on pediatric lung CEUS and to suggest potential additional uses that can be derived from adult studies.

Indexed as

Pleural EffusionPneumoniaAdultChildContrast MediaHumansLungUltrasonographyContrast MediaAbscessChildrenContrast-enhanced ultrasoundEmpyemaLungNecrotizing pneumoniaParapneumonic effusionPneumoniaUltrasound contrast agents

Identifiers

PMID33978798
PMCPMC8566417
OpenAlexW3160441955

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.