Evidence map›Paper›PMID 33978540›Full record

ArticleAutophagy2021

V-ATPase controls tumor growth and autophagy in a Drosophila model of gliomagenesis.

Miriam Formica, Alessandra Maria Storaci, Irene Bertolini, Francesca Carminati, Helene Knævelsrud, Valentina Vaira, Thomas Vaccari

Open access · hybridAbstract read
In one paragraph

Article in Autophagy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. V-ATPase in glioma stem cells: a novel metabolic vulnerability.Journal of experimental & clinical cancer research : CR · 2025
    Article
  3. Article
  4. Article
  5. Circadian GeneInternational journal of molecular sciences · 2022
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Miriam FormicaDepartment of Biosciences, Università Degli Studi Di Milano, Milan, Italy.
Alessandra Maria StoraciDivision of Pathology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Irene BertoliniDivision of Pathology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Francesca CarminatiDepartment of Biosciences, Università Degli Studi Di Milano, Milan, Italy.
Helene KnævelsrudDepartment of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, the Norwegian Radium Hospital, Oslo, Norway.
Valentina VairaDivision of Pathology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Thomas VaccariDepartment of Biosciences, Università Degli Studi Di Milano, Milan, Italy.
University of Milan · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma (GBM), a very aggressive and incurable tumor, often results from constitutive activation of EGFR (epidermal growth factor receptor) and of phosphoinositide 3-kinase (PI3K). To understand the role of autophagy in the pathogenesis of glial tumors

Indexed as

NeoplasmsVacuolar Proton-Translocating ATPasesAnimalsAutophagyDrosophilaDrosophila melanogasterHumansLysosomesPhosphatidylinositol 3-KinasesPhosphatidylinositol 3-KinasesVacuolar Proton-Translocating ATPasesAutophagycancer modelfruit flyglioblastomalysosomesneurospheresref(2)PV-ATPase

Identifiers

PMID33978540
PMCPMC8726678
OpenAlexW3161551664

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.