Evidence map›Paper›PMID 33978398›Full record

ArticleACS applied materials & interfaces2021

Shreyas Kuddannaya, Wei Zhu, Chengyan Chu, Anirudha Singh, Piotr Walczak, Jeff W M Bulte

Open access · greenAbstract read
In one paragraph

Article in ACS applied materials & interfaces, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. In Vivo Imaging of Implanted Hyaluronic Acid Hydrogel Biodegradation.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Shreyas KuddannayaThe Russell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, The Johns Hopkins School of Medicine, Baltimore, Maryland 21205, United States.
Wei ZhuThe Russell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, The Johns Hopkins School of Medicine, Baltimore, Maryland 21205, United States.
Chengyan ChuThe Russell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, The Johns Hopkins School of Medicine, Baltimore, Maryland 21205, United States.
Anirudha SinghDepartment of Urology, the James Buchanan Brady Urological Institute, The Johns Hopkins School of Medicine, Baltimore, Maryland 21287, United States.
Piotr WalczakCenter for Advanced Imaging Research, Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland, Baltimore, Maryland 21201, United States.
Jeff W M BulteThe Russell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, The Johns Hopkins School of Medicine, Baltimore, Maryland 21205, United States.ORCID http://orcid.org/0000-0003-1202-1610
Johns Hopkins University · USUniversity of Maryland, Baltimore · US

Funding

Label-Free Imaging of Composite Hyaluronic Acid Hydrogels in Regenerative MedicineR01EB023647 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI BULTE, JEFF W. · 2017 to 2020
$1.5M
A Durable and Urine-Leakage Resistive Tissue Engineered Urinary DiversionR21EB026711 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI SINGH, ANIRUDHA · 2018 to 2020
$655k
Combined Optical/Micro-CT ScannerS10OD010744 · OD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI BULTE, JEFF W. · 2012 to 2012
$599k
NIBIB NIH HHS R01 EB023647NIBIB NIH HHS R21 EB026711NIH HHS S10 OD010744
6 · The paper itself

Abstract

Transplanted glial-restricted progenitor (GRP) cells have potential to focally replace defunct astrocytes and produce remyelinating oligodendrocytes to avert neuronal death and dysfunction. However, most central nervous system cell therapeutic paradigms are hampered by high initial cell death and a host anti-graft immune response. We show here that composite hyaluronic acid-based hydrogels of tunable mechanical strengths can significantly improve transplanted GRP survival and differentiation. Allogeneic GRPs expressing green fluorescent protein and firefly luciferase were scaffolded in optimized hydrogel formulations and transplanted intracerebrally into immunocompetent BALB/c mice followed by serial

Indexed as

NeurogliaStem CellsAnimalsCell DifferentiationCell SurvivalCell TrackingHyaluronic AcidHydrogelsMagnetic Resonance ImagingMaleMiceMice, Inbred BALB COptical ImagingStem Cell TransplantationHyaluronic AcidHydrogelsbiodegradationBLICEST MRIgelatinglial-restricted progenitorhyaluronic acidhydrogel

Identifiers

PMID33978398
PMCPMC9440547
OpenAlexW3163349527

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.