Evidence map›Paper›PMID 33978234›Full record

ReviewJournal of cutaneous pathology2021

Skin manifestations as potential symptoms of diffuse vascular injury in critical COVID-19 patients.

Afsaneh Sadeghzadeh-Bazargan, Mahdi Rezai, Niloufar Najar Nobari, Samaneh Mozafarpoor, Azadeh Goodarzi

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of cutaneous pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 4 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 29 citations in OpenAlex.

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  16. The effect of opium on severity of COVID-19 infection:An original study from Iran.Medical journal of the Islamic Republic of Iran · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Afsaneh Sadeghzadeh-BazarganDepartment of Dermatology, Rasool Akram Medical Complex, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Mahdi RezaiDepartment of Emergency Medicine Management Research Center, Rasool Akram Medical Complex, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Niloufar Najar NobariDepartment of Dermatology, Rasool Akram Medical Complex, Iran University of Medical Sciences (IUMS), Tehran, Iran.ORCID https://orcid.org/0000-0002-4245-1980
Samaneh MozafarpoorDermatologist, Skin Disease and Leishmaniasis Research Center, Department of Dermatology, Isfahan University of Medical Sciences, Isfahan, Iran.ORCID https://orcid.org/0000-0001-9417-4295
Azadeh GoodarziDepartment of Dermatology, Rasool Akram Medical Complex, Iran University of Medical Sciences (IUMS), Tehran, Iran.ORCID https://orcid.org/0000-0002-1249-4429
Iran University of Medical Sciences · IRIsfahan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a respiratory viral infection caused by a novel coronavirus, COVID-19 became rapidly pandemic within a few months. Despite the wide range of manifestations and organ involvement in COVID-19 patients, the exact pathogenesis of severe and fatal types of COVID-19 and causes involved with the individual base of the disease is not yet understood. Several studies have reported clinical, laboratory, and histopathological data in favor of vascular injury in multiple organs of critically ill patients with COVID-19 as a result of hyperactive immune response, inflammation, and cytokine storm. Also, both clinical and histopathological evidence points to such vascular involvements in the skin. Given the ease of clinical examinations and skin biopsy and the lower risks of transmission of COVID-19 to healthcare workers, the present review article was conducted to investigate the vascular skin manifestations of COVID-19 patients clinically and/or histopathologically as helpful clues for better understanding the pathogenesis and predicting the prognosis of the disease, especially in severe cases.

Indexed as

COVID-19HumansPeripheral Vascular DiseasesSARS-CoV-2SkincoagulopathycoronavirusCOVID-19cytokinehistopathologyinflammationischemianecrosissevere acute respiratory syndrome coronavirus 2 (SARS-COV-2)skinskin biopsy cutaneousskin manifestationvascular injuryvasculitisvasculopathy

Identifiers

PMID33978234
PMCPMC8239514
OpenAlexW3160747878

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.