Evidence map›Paper›PMID 33978095›Full record

ArticleRevista do Instituto de Medicina Tropical de Sao Paulo2021

Prevalence and genetic characterization of Dientamoeba fragilis in asymptomatic children attending daycare centers.

Ana Paula Oliveira-Arbex, Érica Boarato David, Simone Mario Cacciò, Cátia Regina Branco da Fonseca, Joelma Gonçalves Martin, Cilmery Suemi Kurokawa, Fabio Tosini, Jayme Augusto Souza Neto, Semíramis Guimarães

Open access · diamondAbstract read
In one paragraph

Article in Revista do Instituto de Medicina Tropical de Sao Paulo, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Molecular epidemiology and genotype diversity of Dientamoeba fragilis in a Czech hospital-based cohort: higher prevalence in paediatric patients and evidence of mixed G1/G2 infection in a single patient.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  3. Molecular detection ofFood and waterborne parasitology · 2025
    Article
  4. Review
  5. Pathogens (Basel, Switzerland) · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Ana Paula Oliveira-ArbexUniversidade Estadual Paulista, Instituto de Biociências, Departmento de Parasitologia, Botucatu, São Paulo, Brazil.
Érica Boarato DavidUniversidade Estadual Paulista, Instituto de Biociências, Departmento de Parasitologia, Botucatu, São Paulo, Brazil.
Simone Mario CacciòIstituto Superiore di Sanità, Dipartimento Malattie Infettive, Parassitarie ed Immunomediate, Rome, Italy.ORCID http://orcid.org/0000-0002-8561-1323
Cátia Regina Branco da FonsecaUniversidade Estadual Paulista, Faculdade de Medicina, Departamento de Pediatria, Botucatu, São Paulo, Brazil.
Joelma Gonçalves MartinUniversidade Estadual Paulista, Faculdade de Medicina, Departamento de Pediatria, Botucatu, São Paulo, Brazil.
Cilmery Suemi KurokawaUniversidade Estadual Paulista, Faculdade de Medicina, Departamento de Pediatria, Botucatu, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-1380-7527
Fabio TosiniIstituto Superiore di Sanità, Dipartimento Malattie Infettive, Parassitarie ed Immunomediate, Rome, Italy.ORCID http://orcid.org/0000-0003-1120-5725
Jayme Augusto Souza NetoUniversidade Estadual Paulista, Faculdade de Ciências Agronômicas, Departamento de Bioprocessos e Biotecnologia, Botucatu, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-9281-894X
Semíramis GuimarãesUniversidade Estadual Paulista, Instituto de Biociências, Departmento de Parasitologia, Botucatu, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-1415-5209
Universidade Estadual Paulista (Unesp) · BRIstituto Superiore di Sanità · ITUniversidade Paulista · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to provide additional data on the prevalence and genetic diversity of Dientamoeba fragilis in human populations, we conducted a study in children from low-income communities in Sao Paulo State, Brazil. Fecal samples from daycare center attendees up to 6 years old (n=156) and staff members (n=18) were submitted to PCR and sequencing of D. fragilis as well as to microscopic examination for the presence of other intestinal parasites. All children assessed were asymptomatic and 10.3% (16/156) were positive for D. fragilis. No worker was found to be positive. An association between Dientamoeba and coinfection with other intestinal parasites was observed. Concerning the genetic diversity, 14 and only two isolates were genotype 1 and genotype 2, respectively. Our findings outline interesting aspects: (1) asymptomatic children as carriers of Dientamoeba in communities in which environmental conditions ensure parasite transmission and, (2) association between Dientamoeba infection in young children and coinfection with other enteric parasites, reinforcing its transmission via the fecal-oral route.

Indexed as

DientamoebiasisIntestinal Diseases, ParasiticBrazilChildChild, PreschoolDientamoebaFecesHumansPrevalence

Identifiers

PMID33978095
PMCPMC8112823
OpenAlexW3163651067

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.