ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2021
Quality of life of COVID-19 critically ill survivors after ICU discharge: 90 days follow-up.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04411459 (Risk Factors for Prolonged Invasive Mechanical Ventilation in COVID-19 Acute Respiratory Distress Syndrome), which is not on this map. Cited by 39 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Risk Factors for Prolonged Invasive Mechanical Ventilation in COVID-19 Acute Respiratory Distress Syndrome
Who cites it
39 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Factors influencing long-term health-related quality of life among intensive care unit survivors: a mixed-methods systematic review.Frontiers in public health · 2026Pooled it
- Evaluating health-related quality of life in Ethiopia: systematic review and meta-analysis of EQ-5D-based studies.Frontiers in epidemiology · 2024Pooled it
- The health-related quality of life in patients with post-COVID-19 after hospitalization: a systematic review.Revista da Sociedade Brasileira de Medicina Tropical · 2022Pooled it
- Pooled it
- Distinct Health-Related Quality of Life Recovery Trajectories Among ICU Survivors: A Multicentre Prospective Cohort Study Using the EQ-5D-5L.Nursing in critical care · 2026Observational
- The impact of testing positive versus negative for COVID-19 on health-related quality of life: cross-sectional evidence from the Alberta post-COVID-19 follow-up survey.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Health-Related Quality of Life One Year After Intensive Care Unit Admission for COVID-19: A Retrospective, Cross-Sectional, Longitudinal Observational Study.Health science reports · 2025Article
- Physical exercise-related manifestations of long COVID: A systematic review and meta-analysis.Journal of exercise science and fitness · 2024Review
- COVID-19-related health utility values and changes in COVID-19 patients and the general population: a scoping review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Racial and ethnic disparities post-hospitalization for COVID-19: barriers to access to care for survivors of COVID-19 acute respiratory distress syndrome.Scientific reports · 2024Article
- Review
- Prevalence of symptoms of anxiety and depression one year after intensive care unit admission for COVID-19.BMC psychiatry · 2024Article
- Reduced health-related quality of life, fatigue, anxiety and depression affect COVID-19 patients in the long-term after chronic critical illness.Scientific reports · 2024Article
- Post-discharge health assessment in survivors of coronavirus disease: a time-point analysis of a prospective cohort study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Trajectories of health-related quality of life and their predictors in adult COVID-19 survivors: A longitudinal analysis of the Biobanque Québécoise de la COVID-19 (BQC-19).Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Long-Term Impairment in Activities of Daily Living Following COVID-19 in Residents of Long-Term Care Facilities.Medical science monitor : international medical journal of experimental and clinical research · 2023Article
- Quality of Life in COVID-Related ARDS Patients One Year after Intensive Care Discharge (Odissea Study): A Multicenter Observational Study.Journal of clinical medicine · 2023Article
- Characteristics of Mid-Term Post-Intensive Care Syndrome in Patients Attending a Follow-Up Clinic: A Prospective Comparison Between COVID-19 and Non-COVID-19 Survivors.Critical care explorations · 2023Article
- Health-Related Quality of Life for Jordanian-Recovered Individuals During Post-COVID-19 Era: A Cross-Sectional Study.Patient preference and adherence · 2023Article
- Long-term dyspnea, regional ventilation distribution and peripheral lung function in COVID-19 survivors: a 1 year follow up study.BMC pulmonary medicine · 2022Article
Corrections and comments
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Authors and funding
34 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe onset of the coronavirus disease 19 (COVID-19) pandemic in Italy induced a dramatic increase in the need for intensive care unit (ICU) beds for a large proportion of patients affected by COVID-19-related acute respiratory distress syndrome (ARDS). The aim of the present study was to describe the health-related quality of life (HRQoL) at 90 days after ICU discharge in a cohort of COVID-19 patients undergoing invasive mechanical ventilation and to compare it with an age and sex-matched sample from the general Italian and Finnish populations. Moreover, the possible associations between clinical, demographic, social factors, and HRQoL were investigated.
methodsCOVID-19 ARDS survivors from 16 participating ICUs were followed up until 90 days after ICU discharge and the HRQoL was evaluated with the 15D instrument. A parallel cohort of age and sex-matched Italian population from the same geographic areas was interviewed and a third group of matched Finnish population was extracted from the Finnish 2011 National Health survey. A linear regression analysis was performed to evaluate potential associations between the evaluated factors and HRQoL.
results205 patients answered to the questionnaire. HRQoL of the COVID-19 ARDS patients was significantly lower than the matched populations in both physical and mental dimensions. Age, sex, number of comorbidities, ARDS class, duration of invasive mechanical ventilation, and occupational status were found to be significant determinants of the 90 days HRQoL. Clinical severity at ICU admission was poorly correlated to HRQoL.
conclusionCOVID-19-related ARDS survivors at 90 days after ICU discharge present a significant reduction both on physical and psychological dimensions of HRQoL measured with the 15D instrument.
trial registrationNCT04411459.
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