Evidence map›Paper›PMID 33977364›Full record

Trial reportHepatology international2021

Prediction of overt hepatic encephalopathy after transjugular intrahepatic portosystemic shunt treatment: a cohort study.

Yang Yang, Sirui Fu, Bin Cao, Kenan Hao, Yong Li, Jianwen Huang, Wenfeng Shi, Chongyang Duan, Xiao Bai, Kai Tang and 3 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Hepatology international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yang Yang *Zhuhai Interventional Medical Centre, Zhuhai People's Hospital (Zhuhai Hospital Affiliated With Jinan University), No. 79 Kangning Road, Zhuhai, 519000, Guangdong Province, China.
Sirui Fu *Zhuhai Interventional Medical Centre, Zhuhai People's Hospital (Zhuhai Hospital Affiliated With Jinan University), No. 79 Kangning Road, Zhuhai, 519000, Guangdong Province, China.
Bin Cao *Department of General Surgery, Zhuhai People's Hospital (Zhuhai Hospital Affiliated With Jinan University), No. 79 Kangning Road, Zhuhai, China.
Kenan Hao *Division of Vascular and Interventional Radiology, Department of General Surgery, Nanfang Hospital, Southern Medical University, No. 1838 Guangzhou Avenue North, GuangzhouGuangdong Province, 510515, China.
Yong LiZhuhai Interventional Medical Centre, Zhuhai People's Hospital (Zhuhai Hospital Affiliated With Jinan University), No. 79 Kangning Road, Zhuhai, 519000, Guangdong Province, China.
Jianwen HuangZhuhai Interventional Medical Centre, Zhuhai People's Hospital (Zhuhai Hospital Affiliated With Jinan University), No. 79 Kangning Road, Zhuhai, 519000, Guangdong Province, China.
Wenfeng ShiDepartment of General Medicine, Zhuhai People's Hospital (Zhuhai Hospital Affiliated With Jinan University), No. 79 Kangning Road, Zhuhai, China.
Chongyang DuanDepartment of Biostatistics, School of Public Health, Southern Medical University, No. 1838 Guangzhou Avenue North, Guangzhou, China.
Xiao BaiZhuhai Interventional Medical Centre, Zhuhai People's Hospital (Zhuhai Hospital Affiliated With Jinan University), No. 79 Kangning Road, Zhuhai, 519000, Guangdong Province, China.
Kai TangZhuhai Interventional Medical Centre, Zhuhai People's Hospital (Zhuhai Hospital Affiliated With Jinan University), No. 79 Kangning Road, Zhuhai, 519000, Guangdong Province, China.
Shirui YangDepartment of Nuclear Medicine, Zhuhai People's Hospital (Zhuhai Hospital Affiliated With Jinan University), No. 79 Kangning Road, Zhuhai, China.
Xiaofeng HeDivision of Vascular and Interventional Radiology, Department of General Surgery, Nanfang Hospital, Southern Medical University, No. 1838 Guangzhou Avenue North, GuangzhouGuangdong Province, 510515, China. ozonetherapy@126.com.
Ligong LuZhuhai Interventional Medical Centre, Zhuhai People's Hospital (Zhuhai Hospital Affiliated With Jinan University), No. 79 Kangning Road, Zhuhai, 519000, Guangdong Province, China. llg0902@sina.com.

Funding

National Key R&D Program of China No. 2017YFA0205200National Natural Science Foundation of China No. 81771957Nurture Programme of Zhuhai People's Hospital 2019-PY- 07
6 · The paper itself

Abstract

background/purposeOvert hepatic encephalopathy (HE) risk should be preoperatively predicted to identify patients suitable for curative transjugular intrahepatic portosystemic shunt (TIPS) instead of palliative treatments.

methodsA total of 185 patients who underwent TIPS procedure were randomised (130 in the training dataset and 55 in the validation dataset). Clinical factors and imaging characteristics were assessed. Three different models were established by logistic regression analyses based on clinical factors (Model

resultsModel

conclusionOur combination model can successfully predict the risk of overt HE post-TIPS. For the low-risk subgroup, TIPS can be performed safely; however, for the high-risk subgroup, it should be considered more carefully.

Indexed as

Hepatic EncephalopathyPortasystemic Shunt, Transjugular IntrahepaticAdolescentAdultAgedCohort StudiesFemaleHumansLiver CirrhosisMaleMiddle AgedRetrospective StudiesRisk FactorsTreatment OutcomeYoung AdultCalibrationClinical factorCombined modelDecision curveDiscriminationImaging characteristicsNervous system toxicityPreoperative predictionRisk stratificationTIPS

Identifiers

PMID33977364
PMCPMC8286937

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.