Evidence map›Paper›PMID 33977334›Full record

ReviewInternational journal of colorectal disease2021

State-of-the-art colorectal disease: postoperative ileus.

Nils P Sommer, Reiner Schneider, Sven Wehner, Jörg C Kalff, Tim O Vilz

Registry-linked trialOpen access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of colorectal disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05796063 (Postoperative Gastric Point of Care Ultrasound), which is not on this map. Cited by 28 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 5 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05796063 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Postoperative Gastric Point of Care Ultrasound (G-POCUS) in Abdominal Surgery: Can G-POCUS Guidance in Clinical Management of Gastrointestinal Recovery Lead to Better Outcomes?

TypeinterventionalSponsorThomas Jefferson UniversityRan2023 to 2024Enrolled128ConditionsIleus Postoperative, Postoperative Nausea and VomitingArmsgastric point of care ultrasound
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 5 syntheses or guidelines pooled it, 57 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nils P SommerDepartment of Surgery, University Hospital Bonn, Bonn, Germany. nils.sommer@ukbonn.de.ORCID http://orcid.org/0000-0002-1370-1573
Reiner SchneiderDepartment of Surgery, University Hospital Bonn, Bonn, Germany.
Sven WehnerDepartment of Surgery, University Hospital Bonn, Bonn, Germany.
Jörg C KalffDepartment of Surgery, University Hospital Bonn, Bonn, Germany.
Tim O VilzDepartment of Surgery, University Hospital Bonn, Bonn, Germany.
University Hospital Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePostoperative Ileus (POI) remains an important complication for patients after abdominal surgery with an incidence of 10-27% representing an everyday issue for abdominal surgeons. It accounts for patients' discomfort, increased morbidity, prolonged hospital stays, and a high economic burden. This review outlines the current understanding of POI pathophysiology and focuses on preventive treatments that have proven to be effective or at least show promising effects.

methodsPathophysiology and recommendations for POI treatment are summarized on the basis of a selective literature review.

resultsWhile a lot of therapies have been researched over the past decades, many of them failed to prove successful in meta-analyses. To date, there is no evidence-based treatment once POI has manifested. In the era of enhanced recovery after surgery or fast track regimes, a few approaches show a beneficial effect in preventing POI: multimodal, opioid-sparing analgesia with placement of epidural catheters or transverse abdominis plane block; μ-opioid-receptor antagonists; and goal-directed fluid therapy and in general the use of minimally invasive surgery.

conclusionThe results of different studies are often contradictory, as a concise definition of POI and reliable surrogate endpoints are still absent. These will be needed to advance POI research and provide clinicians with consistent data to improve the treatment strategies.

Indexed as

Colorectal NeoplasmsIleusAnalgesics, OpioidHumansLength of StayPostoperative ComplicationsAnalgesics, OpioidEnhanced recoveryFast-trackPerioperative managementPostoperative ileusPrevention

Identifiers

PMID33977334
PMCPMC8346406
OpenAlexW3161711113

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.