Evidence map›Paper›PMID 33977326›Full record

ReviewPlant cell reports2021

CRISPR/Cas systems: opportunities and challenges for crop breeding.

Sukumar Biswas, Dabing Zhang, Jianxin Shi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Plant cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 56 citations in OpenAlex.

  1. Review
  2. Virus-induced systemic and heritable gene editing in pepper (Capsicum annuum L.).The Plant journal : for cell and molecular biology · 2025
    Article
  3. Review
  4. Review
  5. PidTools: Algorithm and web tools for crop pedigree identification analysis.Computational and structural biotechnology journal · 2024
    Article
  6. Drought stress inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2024
    Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Biotechnological Advances to Improve Abiotic Stress Tolerance in Crops.International journal of molecular sciences · 2022
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. An Outlook on Global Regulatory Landscape for Genome-Edited Crops.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sukumar BiswasJoint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Dabing ZhangJoint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Jianxin ShiJoint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China. jianxin.shi@sjtu.edu.cn.ORCID http://orcid.org/0000-0002-7717-0863
Shanghai Jiao Tong University · CN

Funding

Agro-Industry Research and Development Special Fund of China 2016ZX08012-002Agro-Industry Research and Development Special Fund of China 2017ZX08013-001Project 211 B14016
6 · The paper itself

Abstract

Increasing crop production to meet the demands of a growing population depends largely on crop improvement through new plant-breeding techniques (NPBT) such as genome editing. CRISPR/Cas systems are NPBTs that enable efficient target-specific gene editing in crops, which is supposed to accelerate crop breeding in a way that is different from genetically modified (GM) technology. Herein, we review the applications of CRISPR/Cas systems in crop breeding focusing on crop domestication, heterosis, haploid induction, and synthetic biology, and summarize the screening methods of CRISPR/Cas-induced mutations in crops. We highlight the importance of molecular characterization of CRISPR/Cas-edited crops, and pay special attentions to emerging highly specific genome-editing tools such as base editors and prime editors. We also discuss future improvements of CRISPR/Cas systems for crop improvement.

Indexed as

CRISPR-Cas SystemsCrops, AgriculturalGene EditingGenome, PlantHaploidyHybrid VigorMutationPlant BreedingPlants, Genetically ModifiedSynthetic BiologyBase editingCRISPR/Cas9Crop breedingGenome editingMolecular characterizationPrime editing

Identifiers

PMID33977326
OpenAlexW3162544196

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.