Evidence map›Paper›PMID 33977279›Full record

ArticleCell reports. Medicine2021

Comparative immune profiling of acute respiratory distress syndrome patients with or without SARS-CoV-2 infection.

Mikael Roussel, Juliette Ferrant, Florian Reizine, Simon Le Gallou, Joelle Dulong, Sarah Carl, Matheiu Lesouhaitier, Murielle Gregoire, Nadège Bescher, Clotilde Verdy and 15 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Cell reports. Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04373200 (Human Ab Response & immunoMONItoring of COVID-19 Patients), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04373200 nacompletednot on this map

Human Ab Response & immunoMONItoring of COVID-19 Patients

TypeinterventionalSponsorRennes University HospitalRan2020 to 2021Enrolled71ConditionsSARS-CoV-2 Coronavirus, Acute Respiratory Distress SyndromeArmsBlood samples collection, Saliva collection
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

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  15. Distinctive features of severe SARS-CoV-2 pneumonia.The Journal of clinical investigation · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 10 institutions in 3 countries.

Mikael RousselCentre Hospitalier Universitaire de Rennes, Laboratoire Hématologie, Pôle Biologie, 35033 Rennes, France.
Juliette FerrantInstitut national de la santé et de la recherche médicale, Unité Mixte de Recherche U1236, LabEx IGO, Université Rennes 1, Etablissement Français du Sang Bretagne, 35000 Rennes, France.
Florian ReizineInstitut national de la santé et de la recherche médicale, Unité Mixte de Recherche U1236, LabEx IGO, Université Rennes 1, Etablissement Français du Sang Bretagne, 35000 Rennes, France.
Simon Le GallouCentre Hospitalier Universitaire de Rennes, SITI, Pôle Biologie, 35033 Rennes, France.
Joelle DulongCentre Hospitalier Universitaire de Rennes, SITI, Pôle Biologie, 35033 Rennes, France.
Sarah CarlScailyte AG, 6210, Sursee, Switzerland.
Matheiu LesouhaitierInstitut national de la santé et de la recherche médicale, Unité Mixte de Recherche U1236, LabEx IGO, Université Rennes 1, Etablissement Français du Sang Bretagne, 35000 Rennes, France.
Murielle GregoireCentre Hospitalier Universitaire de Rennes, SITI, Pôle Biologie, 35033 Rennes, France.
Nadège BescherCentre Hospitalier Universitaire de Rennes, SITI, Pôle Biologie, 35033 Rennes, France.
Clotilde VerdyCentre Hospitalier Universitaire de Rennes, SITI, Pôle Biologie, 35033 Rennes, France.
Maelle LatourCentre Hospitalier Universitaire de Rennes, SITI, Pôle Biologie, 35033 Rennes, France.
Isabelle BézierCentre Hospitalier Universitaire de Rennes, SITI, Pôle Biologie, 35033 Rennes, France.
Marie CornicCentre Hospitalier Universitaire de Rennes, SITI, Pôle Biologie, 35033 Rennes, France.
Angélique VinitSorbonne Université, UMS037, PASS, Plateforme de Cytométrie de la Pitié-Salpêtrière CyPS, 75013 Paris, France.
Céline MonvoisinInstitut national de la santé et de la recherche médicale, Unité Mixte de Recherche U1236, LabEx IGO, Université Rennes 1, Etablissement Français du Sang Bretagne, 35000 Rennes, France.
Birgit SawitzkiCharité-Universitätsmedizin Berlin, Institut für Medizinische Immunologie, AG Molekulare Immunmodulation, 13353 Berlin, Germany.
Simon LeonardCentre Hospitalier Universitaire de Rennes, Laboratoire Hématologie, Pôle Biologie, 35033 Rennes, France.
Stéphane PaulCentre Hospitalier Universitaire de Saint-Etienne, Laboratoire Immunologie, 42000 Saint-Etienne, France.
Jean FeuillardCentre Hospitalier Universitaire de Limoges, Laboratoire Hématologie, 87000 Limoges, France.
Robin JeannetCentre Hospitalier Universitaire de Limoges, Laboratoire Hématologie, 87000 Limoges, France.
Thomas DaixCentre d'Investigation Clinique INSERM 1435, 87000 Limoges, France.
Vijay K TiwariScailyte AG, 6210, Sursee, Switzerland.
Jean Marc TadiéInstitut national de la santé et de la recherche médicale, Unité Mixte de Recherche U1236, LabEx IGO, Université Rennes 1, Etablissement Français du Sang Bretagne, 35000 Rennes, France.
Michel CognéInstitut national de la santé et de la recherche médicale, Unité Mixte de Recherche U1236, LabEx IGO, Université Rennes 1, Etablissement Français du Sang Bretagne, 35000 Rennes, France.
Karin TarteCentre Hospitalier Universitaire de Rennes, SITI, Pôle Biologie, 35033 Rennes, France.
Inserm · FRÉtablissement Français du Sang · FRCentre Hospitalier Universitaire de Rennes · FRCentre Hospitalier Universitaire de Saint-Étienne · FRCharité - Universitätsmedizin Berlin · DEContrôle de la Réponse Immune B et Lymphoproliférations · FRHôpital Universitaire Dupuytren · FRQueen's University Belfast · GBSorbonne Université · FRUniversité de Limoges · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute respiratory distress syndrome (ARDS) is the main complication of coronavirus disease 2019 (COVID-19), requiring admission to the intensive care unit (ICU). Despite extensive immune profiling of COVID-19 patients, to what extent COVID-19-associated ARDS differs from other causes of ARDS remains unknown. To address this question, here, we build 3 cohorts of patients categorized in COVID-19

Indexed as

AgedCohort StudiesCOVID-19Evolution, MolecularFemaleHLA-DR AntigensHumansIntensive Care UnitsLeukocytes, MononuclearLipopolysaccharide ReceptorsMachine LearningMaleMiddle AgedMonocytesRespiratory Distress SyndromeSARS-CoV-2HLA-DR AntigensLipopolysaccharide ReceptorsSialic Acid Binding Ig-like Lectin 1

Identifiers

PMID33977279
PMCPMC8101789
OpenAlexW3158303768

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.