Evidence map›Paper›PMID 33977256›Full record

ArticleIJU case reports2021

Rare case of immunoglobulin G4-related disease arising in gonadal glands with long-term remission without steroid treatment: Discussion and literature review.

Teruki Isobe, Taku Naiki, Aya Naiki-Ito, Tatsuya Kawai, Toshiki Etani, Takashi Nagai, Satoshi Nozaki, Yuki Kobayakawa, Shoichiro Iwatsuki, Nayuka Matsuyama and 3 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in IJU case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Teruki IsobeDepartment of Nephro-Urology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.
Taku NaikiDepartment of Nephro-Urology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.ORCID https://orcid.org/0000-0002-7638-6048
Aya Naiki-ItoDepartment of Experimental Pathology and Tumor Biology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.
Tatsuya KawaiDepartment of Radiology Graduate School of Medical Sciences Nagoya City University Nagoya Aichi Japan.
Toshiki EtaniDepartment of Nephro-Urology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.
Takashi NagaiDepartment of Nephro-Urology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.
Satoshi NozakiDepartment of Nephro-Urology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.
Yuki KobayakawaDepartment of Nephro-Urology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.
Shoichiro IwatsukiDepartment of Nephro-Urology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.ORCID https://orcid.org/0000-0002-2581-4882
Nayuka MatsuyamaDepartment of Nephro-Urology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.
Hiroyuki KatoDepartment of Experimental Pathology and Tumor Biology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.
Noriyasu KawaiDepartment of Nephro-Urology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.
Takahiro YasuiDepartment of Nephro-Urology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.
Nagoya City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionImmunoglobulin G4-related disease embraces a wide range of extra-pancreatic manifestations. However, localized pathogenesis in gonadal glands, including testes or seminal vesicles, is rare. The clinical course and therapeutic strategy for this disease have not been clearly characterized. CASE PRESENTATION: A 61-year-old Asian male had a left orchiectomy and right seminal vesicle biopsy because of a mass in the left testis and right seminal vesicle. Histological findings showed an infiltration of immunoglobulin G4-positive plasma cells in the respective tissues and met immunoglobulin G4-related disease diagnostic criteria. No recurrence and exacerbation have been observed after 12 years' follow-up without any clinical intervention. To date, immunoglobulin G4-related disease in gonadal tissue is rare. This is the first case with mass-forming lesions in both the testis and seminal vesicle.

conclusionBased on the clinical course of our case and the literature, for patients with accurately diagnosed inactive gonadal immunoglobulin G4-related disease, watchful waiting is a feasible clinical treatment option.

Indexed as

IgG4‐related diseasemalignant lymphomascrotal massseminal vesicletestis

Identifiers

PMID33977256
PMCPMC8088880
OpenAlexW3136166611

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.