Evidence map›Paper›PMID 33977237›Full record

ArticleIJU case reports2021

Relationship between miR-155 expression and clear cell papillary renal cell carcinoma in the dialyzed kidney.

Ei Shiomi, Renpei Kato, Tomohiko Matsuura, Shigekatsu Maekawa, Yoichiro Kato, Mitsugu Kanehira, Ryo Takata, Jun Sugimura, Kazuyuki Ishida, Takaya Abe and 2 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in IJU case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Ei ShiomiDepartment of Urology School of Medicine Iwate Medical University Yahaba Japan.ORCID https://orcid.org/0000-0002-7221-4628
Renpei KatoDepartment of Urology School of Medicine Iwate Medical University Yahaba Japan.
Tomohiko MatsuuraDepartment of Urology School of Medicine Iwate Medical University Yahaba Japan.
Shigekatsu MaekawaDepartment of Urology School of Medicine Iwate Medical University Yahaba Japan.ORCID https://orcid.org/0000-0003-4620-2831
Yoichiro KatoDepartment of Urology School of Medicine Iwate Medical University Yahaba Japan.
Mitsugu KanehiraDepartment of Urology School of Medicine Iwate Medical University Yahaba Japan.
Ryo TakataDepartment of Urology School of Medicine Iwate Medical University Yahaba Japan.
Jun SugimuraDepartment of Urology School of Medicine Iwate Medical University Yahaba Japan.
Kazuyuki IshidaDepartment of Molecular Diagnostic Pathology School of Medicine Iwate Medical University Yahaba Iwate Japan.
Takaya AbeDepartment of Urology School of Medicine Iwate Medical University Yahaba Japan.
Tamotsu SugaiDepartment of Molecular Diagnostic Pathology School of Medicine Iwate Medical University Yahaba Iwate Japan.
Wataru ObaraDepartment of Urology School of Medicine Iwate Medical University Yahaba Japan.
Iwate Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionClear cell papillary renal cell carcinoma often develops in the context of the dialyzed kidney (end-stage renal disease). However, the relationship between clear cell papillary renal cell carcinoma and microRNA expression in patients with end-stage renal disease remains unclear. CASE PRESENTATION: A left renal tumor measuring 22 mm was detected and a radical nephrectomy was performed on a 50-year-old man who had received hemodialysis for the past 6 years. A pathological diagnosis of pT1aNxMx, clear cell papillary renal cell carcinoma was made. We studied the expression of miR-155 in this case and compared it to the expression in nondialysis kidney tissue. The expression level of miR-155 was upregulated in tumor tissue compared with expression levels in the renal cortex for the present case. The expression level of miR-155 in the renal cortex was lower in the present case than in nondialysis kidney tissues.

conclusionWe demonstrated upregulation of miR-155 in a case of clear cell papillary renal cell carcinoma arising from end-stage renal disease.

Indexed as

clear cell papillary renal cell carcinomaESRDmicroRNAmiR‐155mTOR pathway

Identifiers

PMID33977237
PMCPMC8088888
OpenAlexW3138746725

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.