Evidence map›Paper›PMID 33977196›Full record

ReviewJournal of the Endocrine Society2021

COVID-19, an Incentive to Tackle Sugar in Hospitals and at Home.

Anuraag A Vazirani

Abstract readReview
In one paragraph

Review in Journal of the Endocrine Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Anuraag A VaziraniMedical Sciences Division, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0003-3642-3390

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity and metabolic disease are thwarting our efforts to recover from COVID-19. Chronic inflammation is a key feature of both COVID-19 and the metabolic syndrome. Sugar consumption in particular has been shown to affect COVID-19 mortality by contributing to the chronic inflammatory state. Restriction of free sugar intake has a measurable effect on disease-predicting physiological parameters in as little as 9 days. The rapid reduction in inflammation following fructose restriction is key in the context of the COVID-19 pandemic, as COVID-19 exacerbates the same inflammatory pathways as those driven by the metabolic syndrome. Healthcare providers have a duty to implement international recommendations of reduced free sugar intake. By doing so, they could reduce the chronic inflammatory burden contributing to COVID-19 patients' demise. Further, it would set a precedent for reducing the risk of severe disease in the uninfected, by maximizing their potential metabolic health in the context of an infection predicated on its disruption.

Indexed as

coronavirusCOVID-19free sugarmetabolic diseasesmetabolic syndromeobesitysugarsugars

Identifiers

PMID33977196
PMCPMC7989335

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.