Evidence map›Paper›PMID 33976923›Full record

ArticleCentral European journal of urology2021

Erectile function in SRY positive 46,XX males with normal phenotype.

Metin Yiğman, Semih Tangal, Ahmet Hakan Haliloğlu, Gamze Sinem Çağlar

Abstract read
In one paragraph

Article in Central European journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Long-term outcomes in non-CAH 46,XX DSD.Frontiers in endocrinology · 2024
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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Metin YiğmanUfuk University Faculty of Medicine, Department of Urology, Ankara, Turkey.
Semih TangalUfuk University Faculty of Medicine, Department of Urology, Ankara, Turkey.
Ahmet Hakan HaliloğluUfuk University Faculty of Medicine, Department of Urology, Ankara, Turkey.
Gamze Sinem ÇağlarUfuk University Faculty of Medicine, Department of Obtetrics and Gynecology, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe 46,XX male syndrome is a rare disorder of sex development and has two different forms, depending on the sex-determining region's presence on the Y chromosome (SRY) gene. The SRY positive 46,XX males are usually diagnosed during infertility workup. We evaluated the erectile function of 46,XX SRY positive males and compared it with healthy males. MATERIAL AND

methodsTen patients with azoospermia and 46,XX SRY positive disorder who referred to a urology clinic with infertility were analyzed retrospectively. Controls were chosen from healthy males at similar ages. The physical examination was performed, and serum hormones were obtained at admission. The clinical assessment of erectile dysfunction was evaluated by the International Index of Erectile Function (IIEF) questionnaire.

resultsThere was no statistically significant difference between the two groups in terms of age, serum prolactin, luteinizing hormone (LH) levels and IIEF scores (P >0.05). In 46,XX males, serum follicle-stimulating hormone (FSH) levels were significantly higher, and total testosterone levels and testicular volumes were found to be significantly lower when compared to controls (p <0.001, p <0.05, p <0.01, respectively).

conclusionsThis study indicates that these males' erectile function is similar to those of 46,XY males.

Indexed as

46,XX disorders of sex developmentazoospermiaerectile dysfunctiongenesinfertilitysex-determining region on Y chromosome

Identifiers

PMID33976923
PMCPMC8097651

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