Evidence map›Paper›PMID 33976737›Full record

ArticleJournal of Cancer2021

High expression of TREM2 promotes EMT via the PI3K/AKT pathway in gastric cancer: bioinformatics analysis and experimental verification.

Chunmei Li, Xiaoming Hou, Shuqiao Yuan, Yigan Zhang, Wenzhen Yuan, Xiaoguang Liu, Juan Li, Yuping Wang, Quanlin Guan, Yongning Zhou

Open access · goldAbstract read
In one paragraph

Article in Journal of Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. HEYL-mediated activation of LAMA3 influences radiotherapy response in esophageal cancer.Esophagus : official journal of the Japan Esophageal Society · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. TREM2Frontiers in immunology · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Oncogenic transmembrane protein 158 drives the PI3K/Akt signaling pathway to accelerate gastric cancer cell growth.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Chunmei LiDepartment of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou, China.
Xiaoming HouDepartment of Oncology, The First Hospital of Lanzhou University, Lanzhou, China.
Shuqiao YuanDepartment of medical laboratory, The First Hospital of Lanzhou University, Lanzhou, China.
Yigan ZhangThe First School of Clinical Medicine, Lanzhou University, Lanzhou, China.
Wenzhen YuanDepartment of Oncology Surgery, The First Hospital of Lanzhou University, Lanzhou, China.
Xiaoguang LiuDepartment of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou, China.
Juan LiDepartment of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou, China.
Yuping WangDepartment of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou, China.
Quanlin GuanDepartment of Oncology Surgery, The First Hospital of Lanzhou University, Lanzhou, China.
Yongning ZhouDepartment of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou, China.
Lanzhou University · CNFirst Hospital of Lanzhou University · CNGansu Provincial Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

bioinformaticsEMTgastric cancer (GC)PI3K/AKT pathwayTREM2

Identifiers

PMID33976737
PMCPMC8100818
OpenAlexW3155429717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.