Evidence map›Paper›PMID 33976704›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

Opposing and Operated Side Electroacupuncture Generates Similar Analgesic Effects on Pain after Knee Surgery.

Hai Huang, Xiuling Song, Jiayou Wang, Man Xing, Bingxin Kang, Chenghao Ma, Wenbiao Li, Wenjun Han, Lianbo Xiao, Yuelai Chen

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Hai HuangShenzhen Hospital, Shanghai University of Traditional Chinese Medicine, 16 Xiantong Rd. Luohu District, Shenzhen, Guangdong 518004, China.ORCID https://orcid.org/0000-0002-2376-0462
Xiuling SongShanghai University of Traditional Chinese Medicine, 1200 Cailun Rd, Shanghai 201203, China.
Jiayou WangShanghai University of Traditional Chinese Medicine, 1200 Cailun Rd, Shanghai 201203, China.
Man XingShanghai University of Traditional Chinese Medicine, 1200 Cailun Rd, Shanghai 201203, China.
Bingxin KangGuanghua Hospital, Shanghai University of Traditional Chinese Medicine, 540 Xinhua Rd, Shanghai 200052, China.
Chenghao MaGuanghua Hospital, Shanghai University of Traditional Chinese Medicine, 540 Xinhua Rd, Shanghai 200052, China.
Wenbiao LiShanghai University of Traditional Chinese Medicine, 1200 Cailun Rd, Shanghai 201203, China.
Wenjun HanShanghai University of Traditional Chinese Medicine, 1200 Cailun Rd, Shanghai 201203, China.
Lianbo XiaoGuanghua Hospital, Shanghai University of Traditional Chinese Medicine, 540 Xinhua Rd, Shanghai 200052, China.ORCID https://orcid.org/0000-0001-9305-0776
Yuelai ChenShanghai University of Traditional Chinese Medicine, 1200 Cailun Rd, Shanghai 201203, China.ORCID https://orcid.org/0000-0001-7246-9420
Shanghai University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to investigate whether opposing electroacupuncture (EA) could produce similar analgesic effects as operated side EA after knee surgery in rats. Sprague Dawley rats were randomly divided into the sham surgery group, and three surgery groups: opposing EA, operated side EA, and model. After surgery, compared with the sham surgery group, three kinds of pain behavior test methods (mechanical withdrawal threshold (MWT), cumulative pain score [CPS], and mechanical hypersensitivity of knee) were used to assess the pain behavior of the rats in the surgery groups. After knee surgery, the three surgery groups were intervened for three consecutive days: EA on the nonoperated side in the opposing EA group, EA on the operated side in the operated side EA group, and no intervention in the model group. It was shown that MWT was higher and CPS was lower in the two EA groups than in the model group on the first and second days after surgery. On the third day after surgery, MWT in the two EA groups was the highest among the 3 days, CPS was the lowest among the 3 days, and the number of nonvocalizations in rats also increased compared with the model group. Moreover, the MWT of the nonoperated side increased more in the opposing EA group than in the model and operated side EA groups. This indicated that both opposing EA and operated side EA methods can be used to relieve pain after knee joint surgery.

Identifiers

PMID33976704
PMCPMC8087472
OpenAlexW3159826047

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.