Evidence map›Paper›PMID 33976563›Full record

ArticleInternational journal of general medicine2021

Transperineal Parallel Biopsy of the Prostate: A New Approach of Tissue Sampling for Precision Medicine.

Min Qu, Bijun Lian, Yan Wang, Wenhui Zhang, Feng Zhu, Tao Wang, Xiaodong Yue, Zepeng Jia, Huan Chen, Husheng Li and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Min Qu *Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China.
Bijun Lian *Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China.ORCID 0000-0001-9387-2120
Yan Wang *Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China.
Wenhui ZhangDepartment of Urology, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China.
Feng ZhuDepartment of Urology, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China.
Tao WangDepartment of Urology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
Xiaodong YueShanghai Institute for Advanced Communication and Data Science, Shanghai University, Shanghai, People's Republic of China.
Zepeng JiaDepartment of Urology, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China.
Huan ChenDepartment of Urology, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China.
Husheng LiDepartment of Urology, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China.
Jing LiDepartment of Urology, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China.
Xu GaoDepartment of Urology, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China.
Second Military Medical University · CNFirst Affiliated Hospital of Zhengzhou University · CNShanghai University · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThrough an observational study to present a new approach for obtaining high-quality samples for the targeted therapy of prostate cancer. PATIENTS AND

methodsParallel biopsy, which was defined as collecting the tissue from the same site by two biopsies, was performed on patients with elevated PSA. Each tissue was stained by ink to identify the pathological characteristics, including Gleason score and tumor tissue ratio. Kendall tau-b test and intraclass correlation coefficient test were used to compare the consistency between each paired sample. Then, based on the pathology of the biopsies, high-quality tissues would be selected for sequencing, and PyClone model was used to track the clonal evolution.

resultsIn total, 252 pairs of biopsies were collected. The consistency of Gleason score between each paired biopsy is 0.777 (

conclusionParallel biopsy is a reliable approach to collect high-quality tissue and shows potential application in precision medicine.

Indexed as

clonal evolutionary treenext-generation sequencingprecision medicineprostate biopsyprostate cancer

Identifiers

PMID33976563
PMCPMC8104976
OpenAlexW3157525906

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.