ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2021
Risk Factors for Major Amputation in Diabetic Foot Ulcer Patients.
Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diabetic Foot Ulcer Classification Models Using Artificial Intelligence and Machine Learning Techniques: Systematic Review.Journal of medical Internet research · 2025Pooled it
- Monocytes Display Altered Inflammatory Profiles in Individuals with Diabetic Foot Ulcers Indicating Monocyte Dysfunction.European journal of immunology · 2026Article
- Risk factors for re-amputation and major amputation following diabetic foot amputation: a clinical and socioeconomic perspective.BMC surgery · 2026Article
- Development of risk prediction model for major amputation in patients with diabetic foot.BMC endocrine disorders · 2026Article
- Survival analysis of time to amputation following diabetic foot ulcer diagnosis among Indonesians.PloS one · 2026Article
- Cost-effectiveness of ON101 with general wound care for diabetic foot ulcers among patients with type 2 diabetes in Singapore: Analysis of a multi-ethnic country in Asia.Diabetes, obesity & metabolism · 2025Article
- Comparative analysis of the therapeutic effect of antibiotic bone cement on Wagner grade 3 or 4 diabetic foot ulcer in heel and non-heel areas: a retrospective cohort study.Frontiers in endocrinology · 2025Article
- Cost-of-Illness Analysis of Diabetic Foot Ulcer: A Prevalence-Based Approach in Southwest of Iran.Medical journal of the Islamic Republic of Iran · 2025Article
- Promising community nursing effect on diabetic foot patients under the "six-in-one" collaborative management model.American journal of translational research · 2025Article
- Wound management, healing, and early prosthetic rehabilitation: Part 3 - A scoping review of chemical biomarkers.Canadian prosthetics & orthotics journal · 2025Review
- From Ulcer to Amputation: A Systematic Review of Prognostic Models for Diabetic Foot Ulcer Amputation.Risk management and healthcare policy · 2025Review
- Association between tissue loss type and amputation risk among Medicare patients with concomitant diabetes and peripheral arterial disease.Journal of vascular surgery · 2024Article
- Enhancing diabetic foot ulcer prediction with machine learning: A focus on Localized examinations.Heliyon · 2024Article
- Multimodal Identification of Molecular Factors Linked to Severe Diabetic Foot Ulcers Using Artificial Intelligence.International journal of molecular sciences · 2024Article
- New Diagnostic and Therapeutic Approaches in Diabetic Microvascular Complications.Biomedicines · 2024Article
- Cognitive dysfunction in diabetes-related foot complications: A cohort study.Journal of diabetes and metabolic disorders · 2024Article
- Early intervention and care for Diabetic Foot Ulcers in Low and Middle Income Countries: Addressing challenges and exploring future strategies: A narrative review.Health science reports · 2024Article
- Risk Factors for Major Lower Limb Amputation and Effect of Endovascular Revascularization in Patients with Diabetic Foot Wound.Indian journal of orthopaedics · 2024Article
- Factors associated with diabetic foot ulcers and lower limb amputations in type 1 and type 2 diabetes supported by real-world data from the German/Austrian DPV registry.Journal of diabetes · 2024Article
- Wound management, healing, and early prosthetic rehabilitation: Part 2 - A scoping review of physical biomarkers.Canadian prosthetics & orthotics journal · 2024Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of our study was to identify the new and the more specific risk factors for major amputation in patients with diabetic foot ulcer (DFU).
methodsWe used data from the Electronic Medical Record (EMR) database of our hospital from February 2014 to July 2020. Patients with DFU and amputation were included in the study. The logistic regression model was adjusted for demographic characteristics and related comorbidities between major and minor amputation groups.
resultsAmong 3654 patients with DFU, 363 (9.9%) were amputated. Patients with major versus minor amputation, in multivariable logistic regression models, major amputation independent factors included previous amputation history (odds ratio [OR] 2.31 [95% CI 1.17-4.53],
conclusionMajor amputation was associated with previous amputation history, smoking, CAD, Wagner 5, ABI <0.4, HbA1c, Hb, ALB, WBC, and APTT might be a new independent factor. In view of these factors, early prevention and guidance promptly orientated by multidisciplinary is of great significance to reduce the disability rate and economic burden.
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