Evidence map›Paper›PMID 33976354›Full record

Observational studyScientific reports2021

Long-term kidney function of patients discharged from hospital after an intensive care admission: observational cohort study.

Ryan W Haines, Jonah Powell-Tuck, Hugh Leonard, Siobhan Crichton, Marlies Ostermann

Abstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Observational
  3. Article
  4. Review
  5. Observational
  6. Review
  7. Review
  8. Article
  9. Biomarkers in acute kidney injury.Annals of intensive care · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Acute kidney injury.Intensive care medicine · 2023
    Article
  15. Molecular mechanisms of postintensive care syndrome.Intensive care medicine experimental · 2021
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ryan W HainesWilliam Harvey Research Institute, Queen Mary University of London, London, EC1M 6BQ, UK. r.haines@qmul.ac.uk.ORCID 0000-0002-4864-2825
Jonah Powell-TuckDepartment of Critical Care, King's College London, Guy's and St Thomas' NHS Foundation Trust, London, SE1 7EH, UK.
Hugh LeonardDepartment of Renal Medicine, Guy's and St Thomas' NHS Foundation Trust, London, SE1 9RT, UK.
Siobhan CrichtonMRC Clinical Trials Unit at University College London, London, UK.
Marlies OstermannDepartment of Critical Care, King's College London, Guy's and St Thomas' NHS Foundation Trust, London, SE1 7EH, UK.ORCID 0000-0001-9500-9080

Funding

Medical Research Council MR/T000058/1
6 · The paper itself

Abstract

The long-term trajectory of kidney function recovery or decline for survivors of critical illness is incompletely understood. Characterising changes in kidney function after critical illness and associated episodes of acute kidney injury (AKI), could inform strategies to monitor and treat new or progressive chronic kidney disease. We assessed changes in estimated glomerular filtration rate (eGFR) and impact of AKI for 1301 critical care survivors with 5291 eGFR measurements (median 3 [IQR 2, 5] per patient) between hospital discharge (2004-2008) and end of 7 years of follow-up. Linear mixed effects models showed initial decline in eGFR over the first 6 months was greatest in patients without AKI (- 9.5%, 95% CI - 11.5% to - 7.4%) and with mild AKI (- 12.3%, CI - 15.1% to - 9.4%) and least in patients with moderate-severe AKI (- 4.3%, CI - 7.0% to - 1.4%). However, compared to patients without AKI, hospital discharge eGFR was lowest for the moderate-severe AKI group (median 61 [37, 96] vs 101 [78, 120] ml/min/1.73m

Indexed as

Acute Kidney InjuryAdultAgedCritical CareCritical IllnessFemaleGlomerular Filtration RateHumansKidneyMaleMiddle AgedPatient DischargeTime Factors

Identifiers

PMID33976354
PMCPMC8113423

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.