Evidence map›Paper›PMID 33976251›Full record

ArticleScientific reports2021

UVB protective effects of Sargassum horneri through the regulation of Nrf2 mediated antioxidant mechanism.

Eui Jeong Han, Seo-Young Kim, Hee-Jin Han, Hyun-Soo Kim, Kil-Nam Kim, Ilekuttige Priyan Shanura Fernando, Disanayake Mudiyanselage Dinesh Madusanka, Mawalle Kankanamge Hasitha Madhawa Dias, Sun Hee Cheong, Sang Rul Park and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Low-temperature pulverization-specificAnimal cells and systems · 2024
    Article
  5. Loliolide inInternational journal of molecular sciences · 2023
    Article
  6. Article
  7. Antioxidants (Basel, Switzerland) · 2023
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Eui Jeong Han *Research Center for Healthcare and Biomedical Engineering, Chonnam National University, Yeosu, 59626, Republic of Korea.
Seo-Young Kim *Chuncheon Center, Korea Basic Science Institute, Chuncheon, 24341, Republic of Korea.
Hee-Jin HanDepartment of Food Technology and Nutrition, Chonnam National University, Yeosu, 59626, Republic of Korea.
Hyun-Soo KimNational Marine Biodiversity Institute of Korea, Janghang-eup, Seocheon, 33662, Republic of Korea.
Kil-Nam KimChuncheon Center, Korea Basic Science Institute, Chuncheon, 24341, Republic of Korea.
Ilekuttige Priyan Shanura FernandoControl Center for Aquatic Animal Diseases, Chonnam National University, Yeosu, 59626, Republic of Korea.
Disanayake Mudiyanselage Dinesh MadusankaDepartment of Food Technology and Nutrition, Chonnam National University, Yeosu, 59626, Republic of Korea.
Mawalle Kankanamge Hasitha Madhawa DiasDepartment of Food Technology and Nutrition, Chonnam National University, Yeosu, 59626, Republic of Korea.
Sun Hee CheongDepartment of Food Technology and Nutrition, Chonnam National University, Yeosu, 59626, Republic of Korea.
Sang Rul ParkEstuarine and Coastal Ecology Laboratory, Department of Marine Life Sciences, Jeju National University, Jeju, 63243, Republic of Korea.
Young Seok HanNeo Environmental Business Co., Daewoo Technopark, Doyak-ro, Bucheon, 14523, Republic of Korea.
Kyounghoon Lee *Division of Fisheries Science, Chonnam National University, Yeosu, 59626, Republic of Korea. khlee71@jnu.ac.kr.
Ginnae Ahn *Department of Food Technology and Nutrition, Chonnam National University, Yeosu, 59626, Republic of Korea. gnahn@jnu.ac.kr.
Chonnam National University · KRKorea Basic Science Institute · KRJeju National University · KRMarine Biodiversity Institute of Korea · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to evaluate the protective effect of a methanol extract of Sargassum horneri (SHM), which contains 6-hydroxy-4,4,7a-trimethyl-5,6,7,7a-tetrahydrobenzofuran-2(4H)-one (HTT) and apo-9'-fucoxanthinone, against ultraviolet B (UVB)-induced cellular damage in human keratinocytes and its underlying mechanism. SHM significantly improved cell viability of UVB-exposed human keratinocytes by reducing the generation of intracellular reactive oxygen species (ROS). Moreover, SHM inhibited UVB exposure-induced apoptosis by reducing the formation of apoptotic bodies and the populations of the sub-G

Indexed as

AntioxidantsApoptosisBenzofuransCells, CulturedCell SurvivalDNA DamageHeme Oxygenase-1HumansKeratinocytesNF-E2-Related Factor 2Oxidative StressPlant ExtractsReactive Oxygen SpeciesSargassumSignal TransductionTerpenesAntioxidantsapo-9'-fucoxanthinoneBenzofuransHeme Oxygenase-1NF-E2-Related Factor 2Plant ExtractsReactive Oxygen SpeciesTerpenesTranscription Factor RelA

Identifiers

PMID33976251
PMCPMC8113259
OpenAlexW3161863551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.