Evidence map›Paper›PMID 33976224›Full record

ArticleNPJ breast cancer2021

Randomized trial of weight loss on circulating ghrelin levels among breast cancer survivors.

Leah Puklin, Brenda Cartmel, Maura Harrigan, Lingeng Lu, Fang-Yong Li, Tara Sanft, Melinda L Irwin

Open access · goldAbstract read
In one paragraph

Article in NPJ breast cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
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  5. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Leah PuklinYale University School of Public Health, New Haven, CT, USA. leah.puklin@yale.edu.ORCID http://orcid.org/0000-0003-0848-4866
Brenda CartmelYale University School of Public Health, New Haven, CT, USA.
Maura HarriganYale University School of Public Health, New Haven, CT, USA.
Lingeng LuYale University School of Public Health, New Haven, CT, USA.ORCID http://orcid.org/0000-0001-9871-0809
Fang-Yong LiYale University School of Public Health, New Haven, CT, USA.ORCID http://orcid.org/0000-0003-3171-7592
Tara SanftYale Cancer Center, Yale University School of Medicine, New Haven, CT, USA.
Melinda L IrwinYale University School of Public Health, New Haven, CT, USA.
Yale University · USYale Cancer Center · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Pathology Tissue Services Shared ResourceP30CA016359 · NCI · YALE UNIVERSITY · PI DAVID L RIMM · 1985 to 2026
$85.0M
Yale University Clinical and Translational Science Award ProgramUL1TR000142 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$31.8M
The Yale Cancer Prevention and Control Training ProgramT32CA250803 · NCI · YALE UNIVERSITY · PI Melinda L Irwin, Xiaomei Ma · 2020 to 2026
$2.3M
NCATS NIH HHS UL1 TR000142NCATS NIH HHS UL1 TR001863NCI NIH HHS P30 CA016359NCI NIH HHS T32 CA250803
6 · The paper itself

Abstract

Obesity among breast cancer survivors is associated with increased risk for recurrence and mortality. The hormone ghrelin plays a role in initiating appetite and thus regulating body weight. This study aims to determine the effect of a lifestyle intervention on ghrelin levels in breast cancer survivors with a body mass index (BMI) ≥ 25 kg/m

Identifiers

PMID33976224
PMCPMC8113314
OpenAlexW3160241234

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.