ArticleNature communications2021
Lying in wait: the resurgence of dengue virus after the Zika epidemic in Brazil.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.
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Who cites it
54 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Trends in mosquito species distribution modeling: insights for vector surveillance and disease control.Parasites & vectors · 2023Pooled it
- Social Media and the Influence of Fake News on Global Health Interventions: Implications for a Study on Dengue in Brazil.International journal of environmental research and public health · 2023Trial
- Household and community drivers of Aedes aegypti infestation in tropical cities: Guiding community-led interventions.PLoS neglected tropical diseases · 2026Article
- Frequent introductions and climate suitability drive increasing dengue risk in Florida.medRxiv : the preprint server for health sciences · 2026Article
- Mathematical modeling of sequential Dengue-Zika infections: dynamic insights into antibody-dependent enhancement and neutralization effects.Scientific reports · 2026Article
- The CRISPR-Cas toolkit for mosquito-borne virus surveillance: detection, tracing, and discovery.Frontiers in cellular and infection microbiology · 2026Review
- Variations in annual dengue intensities are explained by temperature anomalies.medRxiv : the preprint server for health sciences · 2025Article
- Risk factors predicting dengue hospitalization and disease severity in children and adolescents living in an endemic area of arbovirus transmission in Northeast Brazil (2017-2020).BMC public health · 2025Article
- Global Circulation Dynamics and Its Determinants of Dengue Virus: A Network Evolution and Model Study from 1990 to 2019.Viruses · 2025Article
- Zika virus vaccines and monoclonal antibodies: a priority agenda for research and development.The Lancet. Infectious diseases · 2025Review
- Climate, inter-serotype competition and arboviral interactions shape dengue dynamics in Thailand.Communications biology · 2025Article
- (Re)Emerging Arboviruses of Public Health Significance in the Brazilian Amazon.Microorganisms · 2025Review
- Oral manifestations of dengue virus infection: a scoping review for clinical dental practice.BMC oral health · 2025Article
- The life history and mosquito consumption dynamics of Notonecta indica (Hemiptera: Notonectidae) in eastern Jamaica.Journal of insect science (Online) · 2025Article
- Article
- Trends in dengue incidence and lethality: interrupted time series analysis, Brazil, 2001-2022.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2025Article
- Impact of the COVID-19 pandemic on dengue in Brazil: Interrupted time series analysis of changes in surveillance and transmission.PLoS neglected tropical diseases · 2024Article
- Climate, demography, immunology, and virology combine to drive two decades of dengue virus dynamics in Cambodia.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Envelope Protein-Targeting Zika Virus Entry Inhibitors.International journal of molecular sciences · 2024Review
- Exploring the urban arbovirus landscape in Rio de Janeiro, Brazil: transmission dynamics and patterns of disease spread.Lancet regional health. Americas · 2024Article
Corrections and comments
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Authors and funding
24 authors.
Funding
Abstract
After the Zika virus (ZIKV) epidemic in the Americas in 2016, both Zika and dengue incidence declined to record lows in many countries in 2017-2018, but in 2019 dengue resurged in Brazil, causing ~2.1 million cases. In this study we use epidemiological, climatological and genomic data to investigate dengue dynamics in recent years in Brazil. First, we estimate dengue virus force of infection (FOI) and model mosquito-borne transmission suitability since the early 2000s. Our estimates reveal that DENV transmission was low in 2017-2018, despite conditions being suitable for viral spread. Our study also shows a marked decline in dengue susceptibility between 2002 and 2019, which could explain the synchronous decline of dengue in the country, partially as a result of protective immunity from prior ZIKV and/or DENV infections. Furthermore, we performed phylogeographic analyses using 69 newly sequenced genomes of dengue virus serotype 1 and 2 from Brazil, and found that the outbreaks in 2018-2019 were caused by local DENV lineages that persisted for 5-10 years, circulating cryptically before and after the Zika epidemic. We hypothesize that DENV lineages may circulate at low transmission levels for many years, until local conditions are suitable for higher transmission, when they cause major outbreaks.
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