Evidence map›Paper›PMID 33976129›Full record

ArticleNature communications2021

Molecular engineering of piezoelectricity in collagen-mimicking peptide assemblies.

Santu Bera, Sarah Guerin, Hui Yuan, Joseph O'Donnell, Nicholas P Reynolds, Oguzhan Maraba, Wei Ji, Linda J W Shimon, Pierre-Andre Cazade, Syed A M Tofail and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
8.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 164 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Peptide Sequence Programmed Piezoelectric Response by Supramolecular Self-Assembly.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  9. Article
  10. Review
  11. Review
  12. Open Challenges and Opportunities in Piezoelectricity for Tissue Regeneration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Lateral Piezoelectricity of Alzheimer's Aβ Aggregates.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 4 countries.

Santu BeraGeorge S. Wise Faculty of Life Sciences, Shmunis School of Biomedicine and Cancer Research, Tel Aviv University, Ramat Aviv, Israel.ORCID 0000-0002-4830-552X
Sarah GuerinDepartment of Physics, Bernal Institute, University of Limerick, Limerick, Ireland.ORCID 0000-0002-2442-4022
Hui YuanSchool of Advanced Materials and Nanotechnology, Xidian University, Xi'an, China.
Joseph O'DonnellDepartment of Physics, Bernal Institute, University of Limerick, Limerick, Ireland.ORCID 0000-0002-7474-4788
Nicholas P ReynoldsARC Training Centre in Biodevices, Faculty of Science, Engineering and Technology, Swinburne University of Technology, Melbourne, Victoria, Australia.
Oguzhan MarabaDepartment of Physics, Bernal Institute, University of Limerick, Limerick, Ireland.
Wei JiGeorge S. Wise Faculty of Life Sciences, Shmunis School of Biomedicine and Cancer Research, Tel Aviv University, Ramat Aviv, Israel.ORCID 0000-0001-8982-5460
Linda J W ShimonDepartment of Chemical Research Support, Weizmann Institute of Science, Rehovot, Israel.ORCID 0000-0002-7861-9247
Pierre-Andre CazadeDepartment of Physics, Bernal Institute, University of Limerick, Limerick, Ireland.
Syed A M TofailDepartment of Physics, Bernal Institute, University of Limerick, Limerick, Ireland.
Damien ThompsonDepartment of Physics, Bernal Institute, University of Limerick, Limerick, Ireland. Damien.Thompson@ul.ie.ORCID 0000-0003-2340-5441
Rusen YangSchool of Advanced Materials and Nanotechnology, Xidian University, Xi'an, China. rsyang@xidian.edu.cn.ORCID 0000-0002-4019-4642
Ehud GazitGeorge S. Wise Faculty of Life Sciences, Shmunis School of Biomedicine and Cancer Research, Tel Aviv University, Ramat Aviv, Israel. ehudg@post.tau.ac.il.ORCID 0000-0001-5764-1720
University of Limerick · IETel Aviv University · ILXidian University · CNLa Trobe University · AUWeizmann Institute of Science · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Realization of a self-assembled, nontoxic and eco-friendly piezoelectric device with high-performance, sensitivity and reliability is highly desirable to complement conventional inorganic and polymer based materials. Hierarchically organized natural materials such as collagen have long been posited to exhibit electromechanical properties that could potentially be amplified via molecular engineering to produce technologically relevant piezoelectricity. Here, by using a simple, minimalistic, building block of collagen, we fabricate a peptide-based piezoelectric generator utilising a radically different helical arrangement of Phe-Phe-derived peptide, Pro-Phe-Phe and Hyp-Phe-Phe, based only on proteinogenic amino acids. The simple addition of a hydroxyl group increases the expected piezoelectric response by an order of magnitude (d

Indexed as

Bioelectric Energy SourcesBiomimetic MaterialsBiomimeticsChemical EngineeringCollagenComputer-Aided DesignMicroscopy, Electron, TransmissionMolecular Dynamics SimulationOligopeptidesProtein Conformation, alpha-HelicalReproducibility of ResultsX-Ray DiffractionCollagenOligopeptides

Identifiers

PMID33976129
PMCPMC8113556
OpenAlexW3163628203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.