Evidence map›Paper›PMID 33975942›Full record

ArticlemBio2021

The DnaK/DnaJ Chaperone System Enables RNA Polymerase-DksA Complex Formation in Salmonella Experiencing Oxidative Stress.

Ju-Sim Kim, Lin Liu, Andrés Vázquez-Torres

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Development of heat-shock resistance inApplied and environmental microbiology · 2023
    Article
  11. Article
  12. Article
  13. International journal of molecular sciences · 2023
    Article
  14. Article
  15. Bactericidal Effect ofFrontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ju-Sim KimUniversity of Colorado School of Medicine, Department of Immunology & Microbiology, Aurora, Colorado, USA jusim.kim@cuanschutz.edu andres.vazquez-torres@cuanschutz.edu.ORCID 0000-0001-7926-9560
Lin LiuUniversity of Colorado School of Medicine, Department of Immunology & Microbiology, Aurora, Colorado, USA.
Andrés Vázquez-TorresUniversity of Colorado School of Medicine, Department of Immunology & Microbiology, Aurora, Colorado, USA jusim.kim@cuanschutz.edu andres.vazquez-torres@cuanschutz.edu.ORCID 0000-0002-6181-4185
University of Colorado Denver · USVA Eastern Colorado Health Care System · US

Funding

Molecular determinants of oxidative stress in Salmonella pathogenesisR01AI136520 · NIAID · UNIVERSITY OF COLORADO DENVER · PI Andres Vazquez-Torres · 2018 to 2026
$3.7M
Analysis of regulatory networks in Salmonella pathogenesis.R01AI155493 · NIAID · UNIVERSITY OF COLORADO DENVER · PI VAZQUEZ-TORRES, ANDRES · 2020 to 2024
$2.5M
Molecular Analysis of Bacterial Adaptive Response to Host Reactive SpeciesI01BX002073 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI Andres Vazquez-Torres · 2013 to 2026
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BLRD Research Career Scientist Award ApplicationIK6BX005384 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI VAZQUEZ-TORRES, ANDRES · 2021 to 2025
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BLRD VA I01 BX002073BLRD VA IK6 BX005384NIAID NIH HHS R01 AI136520NIAID NIH HHS R01 AI155493
6 · The paper itself

Abstract

Our previous biochemical approaches showed that the oxidoreductase activity of the DnaJ protein facilitates the interaction of oxidized DksA with RNA polymerase. Investigations herein demonstrate that under biologically relevant conditions the DnaJ- and DksA-codependent activation of the stringent response in

Indexed as

Oxidative StressAnimalsBacterial ProteinsDNA-Directed RNA PolymerasesHSP40 Heat-Shock ProteinsHSP70 Heat-Shock ProteinsMiceMice, Inbred C57BLSalmonella typhimuriumBacterial ProteinsDNA-Directed RNA PolymerasesHSP40 Heat-Shock ProteinsHSP70 Heat-Shock ProteinschaperoneDksADnaJDnaKhydrogen peroxideoxidative stressredoxSalmonella Typhimuriumstringent response

Identifiers

PMID33975942
PMCPMC8262869
OpenAlexW3162699767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.