Evidence map›Paper›PMID 33975919›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

UNC-2 CaV2 Channel Localization at Presynaptic Active Zones Depends on UNC-10/RIM and SYD-2/Liprin-α in

Kelly H Oh, Mia D Krout, Janet E Richmond, Hongkyun Kim

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 34 citations in OpenAlex.

  1. Transsynaptic linking of calcium channels and postsynaptic receptors at a dyadic synapse.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  9. Presynaptic neurons self-tune by inversely coupling neurotransmitter release with the abundance of CaV2 voltage-gated CaProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  10. RIM and RIM-Binding Protein Localize Synaptic CaV2 Channels to Differentially Regulate Transmission in Neuronal Circuits.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  11. Article
  12. Article
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  14. The role of specific isoforms of CaScientific reports · 2023
    Article
  15. Molecular definition of distinct active zone protein machineries for CabioRxiv : the preprint server for biology · 2023
    Article
  16. Active Zone Trafficking of CaV2/UNC-2 Channels Is Independent of β/CCB-1 and α2δ/UNC-36 Subunits.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  17. Proceedings of the National Academy of Sciences of the United States of America · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kelly H OhCenter for Cancer Cell Biology, Immunology, and Infection, Department of Cell Biology and Anatomy, Chicago Medical School, School of Graduate and Postdoctoral Studies, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064.
Mia D KroutDepartment of Biological Science, University of Illinois at Chicago, Chicago, Illinois 60607.
Janet E RichmondDepartment of Biological Science, University of Illinois at Chicago, Chicago, Illinois 60607.
Hongkyun KimCenter for Cancer Cell Biology, Immunology, and Infection, Department of Cell Biology and Anatomy, Chicago Medical School, School of Graduate and Postdoctoral Studies, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064 hongkyun.kim@rosalindfranklin.edu.ORCID https://orcid.org/0000-0002-4879-7122
Rosalind Franklin University of Medicine and Science · USUniversity of Illinois Chicago · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
A genetic study of BK channel trafficking and regulation in C. elegansR01GM125749 · NIGMS · ROSALIND FRANKLIN UNIV OF MEDICINE & SCI · PI KIM, HONGKYUN, RICHMOND, JANET E · 2018 to 2021
$1.4M
Ligand Specificity In Human Glucose Transporters GLUT1-5 and GLUT9R01GM123103 · NIGMS · ROSALIND FRANKLIN UNIV OF MEDICINE & SCI · PI CHOE, JUN-YONG, OPREA, TUDOR I · 2017 to 2020
$1.3M
NIGMS NIH HHS R01 GM123103NIGMS NIH HHS R01 GM125749NIH HHS P40 OD010440
6 · The paper itself

Abstract

Presynaptic active zone proteins couple calcium influx with synaptic vesicle exocytosis. However, the control of presynaptic calcium channel localization by active zone proteins is not completely understood. In a

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCarrier ProteinsIntercellular Signaling Peptides and ProteinsMembrane ProteinsPresynaptic TerminalsSynaptic TransmissionCaenorhabditis elegans ProteinsCarrier ProteinsIntercellular Signaling Peptides and ProteinsMembrane ProteinsSYD-2 protein, C elegansunc-10 protein, C elegansunc-2 protein, C elegansactive zoneC. elegansvoltage-gated calcium channel

Identifiers

PMID33975919
PMCPMC8260173
OpenAlexW3161152361

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.