Evidence map›Paper›PMID 33975872›Full record

ArticleOpen heart2021

Five-year outcomes following left ventricular assist device implantation in England.

Alex Bottle, Puji Faitna, Paul P Aylin, Martin R Cowie

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Open heart, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Alex BottleSchool of Public Health, Faculty of Medicine, Imperial College London, London, UK.ORCID 0000-0001-9978-2011
Puji FaitnaSchool of Public Health, Faculty of Medicine, Imperial College London, London, UK.
Paul P AylinGeneral Practice and Public Health, Imperial College London, London, UK.ORCID 0000-0003-4589-1743
Martin R CowieSchool of Cardiovascular Medicine & Sciences, Faculty of Life Sciences & Medicine, King's College London, London, UK martin.cowie@kcl.ac.uk.ORCID 0000-0001-7457-2552
Imperial College London · GBKing's College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveImplant rates of mechanical circulatory supports such as left ventricular assist devices (LVAD) have steadily increased in the last decade. We assessed the utility of administrative data to provide information on hospital use and outcomes.

methodsUsing 2 years of national hospital administrative data for England linked to the death register, we identified all patients with an LVAD and extracted hospital activity for 5 years before and after the LVAD implantation date.

resultsIn the two index years April 2011 to March 2013, 157 patients had an LVAD implanted. The mean age was 50.9 (SD 15.4), and 78.3% were men. After 5 years, 92 (58.6%) had died; the recorded cause of death was noncardiovascular in 67.4%. 42 (26.8%) patients received a heart±lung transplantation. Compared with the 12 months before implantation, the 12 months after but not including the month of implantation saw falls in total inpatient and day case admissions, a fall in admissions for heart failure (HF), a rise in non-HF admissions, a fall in emergency department visits not ending in admission and a rise in outpatient appointments (all per patient at risk). Postimplantation complications were common in the subsequent 5 years: 26.1% had a stroke, 23.6% had a device infection and 13.4% had a new LVAD implanted.

conclusionsDespite patients' young age, their mortality is high and their hospital use and complications are common in the 5 years following LVAD implantation. Administrative data provide important information on resource use in this patient group.

Indexed as

Heart-Assist DevicesAdolescentAdultAgedAged, 80 and overEnglandFemaleHeart FailureHumansIncidenceMaleMiddle AgedRisk FactorsTime FactorsTreatment OutcomeVentricular Function, Lefthealth careheart failureleft ventricular assist deviceoutcome assessment

Identifiers

PMID33975872
PMCPMC8117985
OpenAlexW3162167091

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.